Protein Alignment D2hgdh and Agps

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_766254.2
• Gene: Agps / 228061
• MGIID: 2443065
• Length: 671
• Species: Mus musculus
• Alignment Length: 579
• Identity: 141/579 - (24%)
• Similarity: 236/579 - (40%)
• Gaps: 142/579 - (24%)

  Fly    32 TTSRTALAATYPAFATTVRTMAGSGAP--------IPELTEITDNVQRGNYATLTDKDV--AHFE 86
            |||:|::..              |.||        :.||.|     .|.:|:...|..|  || .
Mouse   157 TTSKTSINP--------------SEAPPSIVNEDFLQELKE-----ARISYSQEADDRVFRAH-G 201

  Fly    87 QLLGKNFVLTEDLEGYNICFLKRIRGNSKLVLKPGSTAEVAAILKYCNERRLAVVPQGGNTGLVG 151
            ..|.:.|:|.|.:       .:||   ..:|:.|....:|..|:....:..|.::|.||.|.:..
Mouse   202 HCLHEIFLLREGM-------FERI---PDIVVWPTCHDDVVKIVNLACKYNLCIIPIGGGTSVSY 256

  Fly   152 GSVPICDE----IVLSLARLNKVLSVDEVTGIAVVEAGCILENFDQRAREVGLTVPLDLGAKASC 212
            |.:...||    |.|..:::|::|.|||....|.||||...::.:::.:|.|.....:..:....
Mouse   257 GLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQDLERQLKESGYCTGHEPDSLEFS 321

  Fly   213 HIGGNVSTNAGGVRVVRYGNLHGSVLGVEAVLATGQVLDLMSNFKKDNTGYHMKHLFIGSEGTLG 277
            .:||.:||.|.|::...|||:...|:.::.|...| |::..|...:.:||..:.|..:|||||||
Mouse   322 TVGGWISTRASGMKKNIYGNIEDLVVHMKMVTPRG-VIEKSSQGPRMSTGPDIHHFIMGSEGTLG 385

  Fly   278 VVTKLSML---CPHSSRAVNVAFIGLNSFDDVLKTFVSAKRNLGEILSSCELIDERALNTALEQF 339
            |:|:.::.   .|...:..:|||.........|:..  ||:....  :|..|:|.       :||
Mouse   386 VITEATIKIRPTPEYQKYGSVAFPNFEQGVACLREI--AKQRCAP--ASIRLMDN-------QQF 439

  Fly   340 KF-----------LNSPISGFPFYMLIETSGSNGDH----------DEEKI----NQFIGDGMER 379
            :|           ..|.:.|...:.:.:..|.:.:.          |.||:    .|......:.
Mouse   440 QFGHALKPQVSSIFTSFLDGLKKFYITKFKGFDPNQISVATLLFEGDREKVLQHEKQVYDIAAKF 504

  Fly   380 GEIQDGTVTGDPGKV--QEIWKIREMVPLGL----IEKSFCFKYDISLP---LRDF-YNIVDVMR 434
            |.:..|...|..|.:  ..|..||:   |||    |.:||    :.|.|   :.|. .|:.:.:|
Mouse   505 GGLAAGEDNGQRGYLLTYVIAYIRD---LGLEYYVIGESF----ETSAPWDRVIDLCRNVKERIR 562

  Fly   435 ERC-------GPLATV---------VCGYGHLGDSNLHLNVSCEEFNGEIYKRV-EPF-VYEYTS 481
            ..|       .||:|.         .|.|.:..            ||   |:.: :|. |:|:|.
Mouse   563 RECKERGVQFAPLSTCRVTQTYDAGACIYFYFA------------FN---YRGISDPLTVFEHTE 612

  Fly   482 KLK--------GSISAEHGIGFLKKDYLHYSKDPVAIGYMREMKKLLDPNSILNPYKVL 532
            ...        ||:|..||:|.::|.:|..|...|..|.::.:|:.:||::|.....:|
Mouse   613 AAAREEILANGGSLSHHHGVGKIRKQWLKESISDVGFGMLKSVKEYVDPSNIFGNRNLL 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	124/514 (24%)
		FAD_binding_4	115..252	CDD:279851	39/140 (28%)
		FAD-oxidase_C	291..531	CDD:280983	65/300 (22%)
Agps	NP_766254.2	GlcD	213..665	CDD:223354	119/495 (24%)
		FAD_binding_4	219..362	CDD:279851	39/143 (27%)
		FAD-oxidase_C	397..670	CDD:280983	66/305 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810