Protein Alignment D2hgdh and F32D8.12

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001379315.1
• Gene: F32D8.12 / 179506
• WormBaseID: WBGene00009334
• Length: 474
• Species: Caenorhabditis elegans
• Alignment Length: 494
• Identity: 139/494 - (28%)
• Similarity: 224/494 - (45%)
• Gaps: 71/494 - (14%)

  Fly    76 TLTDKDVAHFEQLLGKNFVLTEDLEGYNICFLKR----IRGNSKLVLKPGSTAEVAAILKYCNER 136
            |..:|.:...::::|.:.|.|:  |.....|.:.    |.....:||:|.:..:|:.|||.||:|
 Worm    12 TAIEKSLPDLQKIVGNSSVRTQ--ESVRRQFARDESHFIAPPPAVVLEPTNVEQVSEILKLCNDR 74

  Fly   137 RLAVVPQGGNTGLVGGSVPICDEIVLS---------LARLNKVLSV-DEVTGIAVVEAGCILENF 191
            .:.|||.|..|||.|||:.....|.:|         |...:.|.|| ...|.||:.:|
 Worm    75 AIPVVPFGTGTGLEGGSMSTLGGICISTQQIIGDPVLREQDFVCSVKPSTTRIALNDA------- 132

  Fly   192 DQRAREVGLTVPLDLGAKASCHIGGNVSTNAGGVRVVRYGNLHGSVLGVEAVLATGQVLDLMSNF 256
               .:..||..|:|.||.||  :.|.|:|:|.|...:|||.:..:|:.:|.|||.|.::|.....
 Worm   133 ---IKNSGLFFPVDPGADAS--VCGMVATSASGTNAIRYGTMKENVVNLEVVLADGTIIDTKGKG 192

  Fly   257 ---KKDNTGYHMKHLFIGSEGTLGVVTKLSMLCPHSSRAVNVAFIGLNSFDDVLKTFVSAKRNLG 318
               :|.:.|::...||:|||||||::|:.::......:.::.|.....:..:...|.|
 Worm   193 RCPRKSSAGFNFTELFVGSEGTLGIITEATVKVHPRPQFLSAAVCSFPTVHEAASTVV------- 250

  Fly   319 EIL------SSCELIDERALNTALEQFKFLN---SPISGFPFYMLIETSGSNGDHDEEKINQ--F 372
            |:|      :..||:|...:. |...:..||   ||.      :.||..|||   ::|..:|  .
 Worm   251 EVLQWNIPVARIELLDTVQIQ-ACNSYSSLNLRESPT------LFIEFHGSN---EKEVADQTSA 305

  Fly   373 IGDGMERGEIQDGTVTGDPGKVQEIWKIRE---MVPLGLIEKSFCFKYDISLPLRDFYNIVDVMR 434
            :.|..:..|..|......|.|...:||.|.   ...|.:...:..|..|:.:|:....:::...|
 Worm   306 VEDICKSHEALDFDSGASPDKRATLWKARHNAYYAALAMRTGARGFTTDVCVPISKLADVISETR 370

  Fly   435 ERCGP---LATVVCGYGHLGDSNLHLNVSCEEFNGEIYKRVEPF---VYEYTSKLKGSISAEHGI 493
            .....   |.|||   ||:||.|.|:.:...|.:...:::::.|   :........|:.:.||||
 Worm   371 SDLDEHEILGTVV---GHVGDGNFHVILPTIEEDKTEHRKIQSFSDRLVRRALAADGTCTGEHGI 432

  Fly   494 GFLKKDYLHYSKDPVAIGYMREMKKLLDPNSILNPYKVL 532
            |..|:.||........:..|..:|..||||:|:||.|||
 Worm   433 GLGKRKYLREELGENTVRLMHTIKHALDPNNIMNPGKVL 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	135/483 (28%)
		FAD_binding_4	115..252	CDD:279851	52/146 (36%)
		FAD-oxidase_C	291..531	CDD:280983	63/259 (24%)
F32D8.12	NP_001379315.1	PLN02805	<43..472	CDD:178402	132/461 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216115at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100306
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820