Protein Alignment D2hgdh and ads-1

DIOPT Version :9

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_497185.1
• Gene: ads-1 / 175192
• WormBaseID: WBGene00000081
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 115/529 - (21%)
• Similarity: 211/529 - (39%)
• Gaps: 110/529 - (20%)

  Fly    49 VRTMAGSGAPIPELTEITDNVQRGNYATLTDKDVAHFEQLLGKNFVLTEDLEGYNICFLKRIRGN 113
            :|.|.|.|..:.::.    |::.|....|.|
 Worm   110 IRLMRGHGHTVHDMI----NLREGKIPRLPD---------------------------------- 136

  Fly   114 SKLVLKPGSTAEVAAILKYCNERRLAVVPQGGNTGLVGG-SVPICDE---IVLSLARLNKVLSVD 174
              :|:.|.|..|:..|::.......|::|.||.|.:... ..|..::   |.:.:|.|:|:|.:|
 Worm   137 --IVVWPKSEHEIVKIIEGAMSHNCAIIPIGGGTSVTNALDTPETEKRAVISMDMALLDKILWID 199

  Fly   175 EVTGIAVVEAGCILENFDQRAREVGLTVPLDLGAKASCHIGGNVSTNAGGVRVVRYGNLHGSVLG 239
            ........:||.:.::.:::..:.|.|...:..:.....:||.|||.|.|::..:|||:...|:.
 Worm   200 RENLTCRAQAGIVGQSLERQLNKKGFTCGHEPDSIEFSTLGGWVSTRASGMKKNKYGNIEDLVVH 264

  Fly   240 VEAVLATGQVLDLMSNFKKDNTGYHMKHLFIGSEGTLGVVTKLSML---CPHSSRAVNVAF---- 297
            :..|...| ::.......:.::|..:..:.:|||||||||:::::.   .|...|..:..|
 Worm   265 LNFVCPKG-IIQKQCQVPRMSSGPDIHQIILGSEGTLGVVSEVTIKIFPIPEVKRFGSFVFPNFE 328

  Fly   298 IGLNSFDDV-LKTFVSAKRNLGEILSSCELIDERALNTALEQ-FKFLNSPIS--------GFPF- 351
            .|:|.|.:| ::....|...|   :.:.:.:..:||..|.:. :..|.|.:|        ||..
 Worm   329 SGVNFFREVAIQRCQPASLRL---MDNDQFVMGQALKVASDSWWADLKSSVSKMYITSWKGFKVD 390

  Fly   352 -----YMLIETSGSNGDHDEEKIN----QFIGDGMERGEIQDGTVTGDPGKVQEIWKIREMVPLG 407
                 ..:.|.:....|..||::|    ||.|       :..|...|..| .:..:.|..:..||
 Worm   391 EICAATCVYEGNREEVDQHEERLNKLAEQFHG-------VVGGAENGQYG-YRLTFAIAYLRDLG 447

  Fly   408 LIEKSFCFKYDISLP----LRDFYNIVDVMRERC---GPLATVV-------------CGYGHLGD 452
            :........::.|:|    |....|:.::|:...   |....|:             |.|.:.|.
 Worm   448 MNHGVLGESFETSVPWDKVLSLCRNVKELMKREAKAQGVTHPVLANCRVTQVYDAGACVYFYFGF 512

  Fly   453 SNLHLNVSCEEFNG-EIYKRVEPFVYEYTSKLKGSISAEHGIGFLKKDYLHYSKDPVAIGYMREM 516
            :...|.      || |:|.|:|....:......||||..||:|.::|.::..:...|.|..::.:
 Worm   513 NARGLK------NGLEVYDRIETAARDEIIACGGSISHHHGVGKIRKQWMLTTNGAVGIALLKAI 571

  Fly   517 KKLLDPNSI 525
            |..|||.:|
 Worm   572 KSELDPANI 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	85..532	CDD:223354	107/493 (22%)
		FAD_binding_4	115..252	CDD:279851	34/140 (24%)
		FAD-oxidase_C	291..531	CDD:280983	62/280 (22%)
ads-1	NP_497185.1	GlcD	92..581	CDD:223354	115/529 (22%)
		FAD_binding_4	135..276	CDD:279851	35/177 (20%)
		FAD-oxidase_C	313..581	CDD:280983	63/285 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810