Protein Alignment D2hgdh and Agps

DIOPT Version :10

• Sequence 1: NP_569982.1
• Gene: D2hgdh / 31184
• FlyBaseID: FBgn0023507
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_061499652.1
• Gene: Agps / 1274507
• VectorBaseID: AGAMI1_012469
• Length: 626
• Species: Anopheles gambiae
• Alignment Length: 553
• Identity: 138/553 - (24%)
• Similarity: 216/553 - (39%)
• Gaps: 143/553 - (25%)

  Fly    84 HFEQLLGKNF--VLTEDLEGYNI---------C--FLKRIRGNS--------------------- 114
            ||...:.:||  .|::..||..:         |  ||..|||:.
Mosquito    82 HFRDYVIENFNVDLSDRREGVPVPNEYPAPVPCPEFLADIRGHGIDCTQNGEDRLIRCHGQTLHD 146

  Fly   115 -------------KLVLKPGSTAEVAAILKYCNERRLAVVPQGGNTGLVGGSVPICDE------I 160
                         .:||.|.|..:|..|::..|:|.:.::|.||.|. |.||| .|.|      .
Mosquito   147 VHMMRTGTFKRIPDVVLFPTSHEQVEQIVQSANKRNVVLIPYGGGTS-VSGSV-TCPEGETRPIA 209

  Fly   161 VLSLARLNKVLSVDEVTGIAVVEAGCILENFDQRAREVGLTVPLDLGAKASCHIGGNVSTNAGGV 225
            .|..:::|::|.:|....:|..|||.:.::.::..|::|.||..:..:.....:||.|:|.|.|:
Mosquito   210 ALDTSQMNRMLWIDRQNLVACFEAGIVGQDLERELRQLGFTVGHEPDSYEFSTLGGWVATRASGM 274

  Fly   226 RVVRYGNLHGSVLGVEAVLATGQVLDLMSNFKKDNTGYHMKHLFIGSEGTLGVVTKLSML---CP 287
            :...|||:...::.|:.|.:.| ||:......:.:.|....||.:||||||||:|::.:.   .|
Mosquito   275 KKNVYGNIEDLLVRVKMVTSKG-VLERSLAVPRVSCGPDFNHLVLGSEGTLGVITEVVIKIRPLP 338

  Fly   288 HSSRAVNVAFIGLNSFDDVLKTFVSAKRNLGEIL------SSCELIDERALNTALEQFKFLNS-P 345
            ...|..::.|          ..|.|..|.|.|:.      :|..|||.       |||.|..: .
Mosquito   339 QVKRYGSLVF----------PDFGSGIRCLREVARERLQPASIRLIDN-------EQFVFGQALK 386

  Fly   346 ISGFPFYMLIETSGSNGDHDEEKINQFIGDGMERGEI------------QDGTVTGDPGKVQEIW 398
            |.|.|    :.|.|       ||:.:......:|.::            .|..|.....|:..|.
Mosquito   387 IPGGP----LATVG-------EKLKKVYLTRWKRLQLDRIAIATLLFEGHDAQVKQHEAKIFAIA 440

  Fly   399 KIREMVPLGLI--EKSFCFKYDISLPLRDF---YNIV------DVMRERCGPLATVV--CGYGHL 450
            |.......|..  ||.:...:.|:. :||.   |:||      .|..:||..|.|.|  |.....
Mosquito   441 KRYGGFSAGSSNGEKGYILTFVIAY-IRDLALDYSIVAESFETSVSWDRCEALCTNVKSCVRKEC 504

  Fly   451 GDSNL-HLNVSCE---------------EFNG-------EIYKRVEPFVYEYTSKLKGSISAEHG 492
            ...|: |..:||.               .||.       .||:.:|....:......||||..||
Mosquito   505 AKHNIQHYLISCRVTQTYDAGACVYFYFGFNHAGFSNPVTIYEEIENKARDEILASGGSISHHHG 569

  Fly   493 IGFLKKDYLHYSKDPVAIGYMREMKKLLDPNSI 525
            :|.::..:...|...|.:...:..|:.||||:|
Mosquito   570 VGKIRSRWYPQSVSDVGVQLYKATKRELDPNNI 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
D2hgdh	NP_569982.1	GlcD	77..533	CDD:440046	138/553 (25%)
Agps	XP_061499652.1	None