Protein Alignment ph-p and Scm

DIOPT Version :10

• Sequence 1: NP_476871.2
• Gene: ph-p / 31181
• FlyBaseID: FBgn0004861
• Length: 1589
• Species: Drosophila melanogaster
• Sequence 2: NP_731385.1
• Gene: Scm / 41168
• FlyBaseID: FBgn0003334
• Length: 877
• Species: Drosophila melanogaster
• Alignment Length: 1195
• Identity: 209/1195 - (17%)
• Similarity: 364/1195 - (30%)
• Gaps: 450/1195 - (37%)

  Fly   475 TTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLN 539
            :.::|:...:..||||.|..:.|.|:.:..::.|      |....:..||
  Fly    29 SASASSTSTSASPGSTTSPASTQRQRGRPAKRAT------CTWCGEGKLP--------------- 72

  Fly   540 AGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQT 604
                    :.:.|....|.:.|.....|...:...::|..           ||.:.:|:   ...
  Fly    73 --------LQYVLPTQTGKKEFCSETCIAEFRKAYSKGAC-----------TQCDNVIR---DGA 115

  Fly   605 PTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAP------- 662
            |.|....:..:...|::       ...|:....:.:...|.:.:::|.|:....|..|
  Fly   116 PNKEFCSIMCMNKHQKK-------NCSTRHSGGSASGKGLAESERKLLASGAPAPTGPFQYESFH 173

  Fly   663 ------VMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAG------ 715
                  .:...|::..||...  :.|||......|:..|.:.:.|...| .|.|..|.|
  Fly   174 VFDWDAYLEETGSEAAPAKCF--KQAQNPPNNDFKIGMKLEALDPRNVT-STCIATVVGVLGSRL 235

  Fly   716 ---------QN-----------KVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQN 760
                     ||           ..:||.     ::....||..:   |.:|...|..|....:.|
  Fly   236 RLRLDGSDSQNDFWRLVDSTEIHAIGHC-----EKNGGMLQPPL---GFRMNASSWPGYLCKILN 292

  Fly   761 GQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQ--QQIAAIQMQQQQ----AAVQAQQQQQQQ 819
                :|..|..        ::||.:....::.:.:  |::.|:..:..|    |.|.|.:..|..
  Fly   293 ----NAMVAPE--------EIFQPEPPEPEENLFKVGQKLEAVDKKNPQLICCATVDAIKDDQIH 345

  Fly   820 VSQQ------------------------QQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQA 860
            |:..                        :..:..|......:..:.:..|:..|.:...||::
  Fly   346 VTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQPPGHKSRMDSSSSKQRCPRPRYTVVAES-- 408

  Fly   861 QHQQALANATQQILQVAPN----QFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQ 921
               :|:..|:.......||    .||.:                       :::...|.....|
  Fly   409 ---EAMVPASPATAHFHPNCKGGPFINN-----------------------SKLPCMVTGPTYQ- 446

  Fly   922 QQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSS---TTPAG----IAT 979
                     .:.::.:|:..|.|..|.           |||.:.|::...   .|.||    :..
  Fly   447 ---------TLAKLCLQEVLAASTDTQ-----------QLSKLLFALEGDVHIVTAAGKNFTVKI 491

  Fly   980 SSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQH 1044
            .|.::.....|.|.|......||.:.:...|:|..|.:..            :.|.::..|:.|
  Fly   492 PSPMRMKDDESLAQFIETLCTTCRACANLISLVHETEECK------------KCANSRKRQLTQ- 543

  Fly  1045 QQLISATIAGGTQQQPQGPPSLTPTTNPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQL 1109
                                |.||.::|:||  ...|.               .|.:.|:||.:.
  Fly   544 --------------------SATPPSSPVLA--DKRNR---------------QSNSATTSPSEK 571

  Fly  1110 VLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEAS 1174
            ::                      |...|.       |:||..|...:|.....||       :.
  Fly   572 II----------------------KQELAV-------KSPVESKSKTSTNNGKEPA-------SQ 600

  Fly  1175 SSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSA-- 1237
            .::..:|:|.:.|             .||.||..|   ..:.||..:       |...|.|.|
  Fly   601 QNSNHSLNNNNNS-------------ASKSSNKVV---IKSEPNGAN-------AQTSSTTQALR 642

  Fly  1238 -------TSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKD 1295
                   .:|:|.::.||  |...|:.:|.|||            :.|:|::|::::|::.||.:
  Fly   643 KVRFQHHANTNTNSSATN--GNQDTSQTTHVST------------SHCSSSSTSSSTSLAGGSAN 693

  Fly  1296 LPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAPGS 1360
                       |..|..::.....|..|    ..|:...|:...|...|:.....|....|.|.:
  Fly   694 -----------TSTIGKYLAPLVAEVHP----EQANVKPSNSYYKSPTTLSSSASLPTSVSTPFT 743

  Fly  1361 DMVACEQCGKMEHKAKLKRKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDE 1425
                                     ||.           |..:..|..||:....|
  Fly   744 -------------------------GCQ-----------SASSTALAAGGVTAAKA--------- 763

  Fly  1426 AMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAAISA-PSPLAMPLGSPLSVALPTLAPLS 1489
                                          .:.|..||.:| .||....:.||:|
  Fly   764 ------------------------------ATAPAGAAATAGASPSYTAITSPVS---------- 788

  Fly  1490 VVTSGAAPKSSEVNGTDRPPISSWSVDDVSNFIRELPGCQD-----YVDDFIQQEIDGQALLLLK 1549
                  .|.|:..|...|.....|::::|..:|..    .|     :.|.|.:.||||:|||||.
  Fly   789 ------TPTSALANSHLRSQPIDWTIEEVIQYIES----NDNSLAVHGDLFRKHEIDGKALLLLN 843

  Fly  1550 EKHLVNAMGMKLGPALKIVAKVESI 1574
            .:.::..||:||||||||...|..:
  Fly   844 SEMMMKYMGLKLGPALKICNLVNKV 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	DUF5585	1015..>1232	CDD:465521	35/216 (16%)
		SAM_Ph1,2,3	1508..1576	CDD:188976	26/72 (36%)
Scm	NP_731385.1	zf-FCS	58..95	CDD:428958	8/65 (12%)
		MBT_dScm_rpt1	196..294	CDD:439097	22/110 (20%)
		MBT_dScm_rpt2	312..383	CDD:439100	9/70 (13%)
		SLED	418..522	CDD:463469	23/147 (16%)
		SAM_Scm	800..870	CDD:188977	27/73 (37%)