Protein Alignment ph-p and Phc2

DIOPT Version :9

• Sequence 1: NP_476871.2
• Gene: ph-p / 31181
• FlyBaseID: FBgn0004861
• Length: 1589
• Species: Drosophila melanogaster
• Sequence 2: NP_001013187.2
• Gene: Phc2 / 313038
• RGDID: 1307912
• Length: 850
• Species: Rattus norvegicus
• Alignment Length: 953
• Identity: 252/953 - (26%)
• Similarity: 378/953 - (39%)
• Gaps: 224/953 - (23%)

  Fly   738 VVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQ--QQQLQLF------QKQQILQQQQML 794
            |.:.:....:..:|:||     |..:..::::.|...:  ..|:.::      |..|::||....
  Rat     7 VPHTSSRASITTNTSGT-----NSSSGCSSSSGGGSGRPTAPQISVYSGIPDRQTVQVIQQALHR 66

  Fly   795 QQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQV-AQA 858
            |...||..:||..||.|.....|....|||.:::.|.|::|..|||...|.:|.......| :||
  Rat    67 QPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVANRQGSTSGSSVSSQA 131

  Fly   859 QAQHQQ---ALANATQQILQVAP--NQFITSHQQQQQQQLHN----QLIQQQLQQQAQAQ----- 909
            .||...   |.:.|..|::..|.  |....|...||...|.|    .|...|.|...:||
  Rat   132 PAQSSSLNLAASPAAAQLINRAQSVNSATASGLAQQAVLLGNTSSPALTASQAQMYLRAQMLIFT 196

  Fly   910 -------VQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFS 967
                   ||.::...:..:.....|.||:               |.:.||...:.....:|.|
  Rat   197 PTATVATVQPELGTGSPARPPTPAQVQNL---------------TLRTQQTPAAAAAAAASGP-- 244

  Fly   968 VSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSS------ 1026
              :.|.|  :..|.||:...|:|..:..|.:..|....||..:..::|:..:.||.|..
  Rat   245 --APTQP--VLPSLALKPTPSSSQPLPPTPQGRTVVQGSPVGAKPSVTDNVTEPLKTDGNSNMEA 305

  Fly  1027 ----------TVASIQQAQTQSAQVHQHQQLISAT--------IAGGTQQQPQGPPSLTP--TTN 1071
                      |||:.|.......|:..||.|...:        :|   ||||| ||..||  .:.
  Rat   306 RPGPDRATVPTVATHQLTAPAYTQLQPHQLLPQPSSKHPQPQFVA---QQQPQ-PPRPTPQVQSQ 366

  Fly  1072 PILAMTS----MMNATVGHLSTAPPVTVSV---TSTAVTSSPG--QLVLLSTASSGGGGSIPATP 1127
            |.||..|    :..:..||.....|||.::   .|||....||  |...|.|..||.....|
  Rat   367 PQLAAVSPSLALQPSPEGHAMPLGPVTQALPLQCSTAHVHKPGSSQQCHLPTPDSGSQNGHP--- 428

  Fly  1128 TKETPSKGP------TATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDA 1186
              |..|..|      |:.::....|.:||        |:...|......|.|..|.
  Rat   429 --EGVSHAPQRRFQHTSAVILQLQPASPV--------PQQCAPDDWKEVVPAEKSV--------- 474

  Fly  1187 SDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIG 1251
                     ..|.|.......|:   .:..|..:.|.:.|.:..|    .|..|        |.|
  Rat   475 ---------PVTRPGLSPHQQAI---ITAIPGGLPGPKSPNIQQC----PAHET--------GQG 515

  Fly  1252 VARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQ 1316
            :..         |.|..:|.|....:..|.::.|.::..||....|:|::||.:|||||:||:||
  Rat   516 IVH---------ALTDLSSPGMTSGNGNSASSITGTAPQNGENKPPQAIVKPQILTHVIEGFVIQ 571

  Fly  1317 EANEPFPVTR---------QRYADKDVSDEPPKKKATMQEDIKLS----GIASAPGSDM-VACEQ 1367
            |..|||||.|         ::||...:.::.|::..|...|.::.    ..:...|:.: :.||.
  Rat   572 EGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCEL 636

  Fly  1368 CGKMEHKAKLKR-KRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEK 1431
            ||:::...|.|| ||:||..|:::.     .||..:..||...           ||       .|
  Rat   637 CGRVDFAYKFKRSKRFCSMACAKRY-----NVGCTKRVGLFHS-----------DR-------SK 678

  Fly  1432 MQTEATPKLSE------SFPILGASTEVPP---MSLPVQAAIS-APSPLAMPLGSPLSVALPTLA 1486
            :|...|...:.      |.|.|...|:..|   :.|.|.||:. |.|.......|..|.....|:
  Rat   679 LQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLS 743

  Fly  1487 PLSVVTSGAAPKS-------SEVNGTD-----------RPPISSWSVDDVSNFIRELPGCQDYVD 1533
            |:|..:|.:..:.       |:::..|           .|  :.|:|:||..|||.|||||:..:
  Rat   744 PISASSSTSRRRQGQRDLELSDMHMRDLVGMGHHFLPSEP--TKWNVEDVYEFIRSLPGCQEIAE 806

  Fly  1534 DFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKE 1576
            :|..|||||||||||||.||::||.:||||||||.|::..:|:
  Rat   807 EFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKD 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	SAM_Ph1,2,3	1508..1576	CDD:188976	40/67 (60%)
		SAM	1511..1576	CDD:197735	39/64 (61%)
Phc2	NP_001013187.2	PHC2_SAM_assoc	662..780	CDD:293222	28/135 (21%)
		SAM_Ph1,2,3	781..849	CDD:188976	40/69 (58%)
		SAM	783..850	CDD:197735	41/69 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7650
eggNOG	1	0.900	-	-		E1_28JS2
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9024
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12247
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.910