DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ph-p and L3mbtl3

DIOPT Version :9

Sequence 1:	NP_476871.2	Gene:	ph-p / 31181	FlyBaseID:	FBgn0004861	Length:	1589	Species:	Drosophila melanogaster
Sequence 2:	NP_001346183.1	Gene:	L3mbtl3 / 237339	MGIID:	2143628	Length:	883	Species:	Mus musculus

Alignment Length:	294	Identity:	69/294 - (23%)
Similarity:	112/294 - (38%)	Gaps:	88/294 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1323 PVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKRKRYCSPGC 1387
            |.||:::|:....|...||    :.::|.|..|.....:.....|  :.:...::::.::..|
Mouse   627 PETREKHANNFKEDSEKKK----ENEVKTSAEAKVVREEPTPSVQ--QSQPPQQVQQVQHAQP-- 683

  Fly  1388 SRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEA-MAEEKMQTEATPKLSESFPILGAST 1451
            .:||:                             :..:| .|::..|.:..|:..:        |
Mouse   684 PQQAQ-----------------------------KAPQAQQAQQAQQAQQAPQAPQ--------T 711

  Fly  1452 EVPPMSLPVQAAISAPS-------------PLAMPLGSPLSV--ALPTLAPLSVVTSGAAPKSSE 1501
            ..|..:..||.|..||.             ..|.|:..|..|  |.||  .....|...|.:.|.
Mouse   712 PQPQQAPQVQQAQQAPQAQQAQQPQQAQQPQQAPPVQQPQQVQQAQPT--QQQAQTQQQAQRRSA 774

  Fly  1502 VNGTDRPPI-------------------------SSWSVDDVSNFIRELPGCQDYVDDFIQQEID 1541
            |..:.:|||                         |.||.|:||.||:.||||:::...|..::||
Mouse   775 VFLSFKPPIPCLPLRWEQQSKLLPTVAGIPASRVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQID 839

  Fly  1542 GQALLLLKEKHLVNAMGMKLGPALKIVAKVESIK 1575
            |:|.||:.:..:|..|.:||||||||...:...|
Mouse   840 GEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFK 873

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	SAM_Ph1,2,3	1508..1576	CDD:188976	33/93 (35%)
ph-p	NP_476871.2	SAM	1511..1576	CDD:197735	30/65 (46%)
L3mbtl3	NP_001346183.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	146..223
		MBT 1	232..332
		MBT	236..332	CDD:214723
		MBT 2	340..439
		MBT	343..439	CDD:214723
		MBT 3	448..543
		MBT	451..543	CDD:214723
		zf-C2HC	558..586	CDD:366692
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	595..768		33/187 (18%)
		SAM_Scm-like-3MBT3,4	808..873	CDD:188981	29/64 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910