Protein Alignment ph-p and phc1

DIOPT Version :10

• Sequence 1: NP_476871.2
• Gene: ph-p / 31181
• FlyBaseID: FBgn0004861
• Length: 1589
• Species: Drosophila melanogaster
• Sequence 2: XP_031761253.1
• Gene: phc1 / 100488113
• XenbaseID: XB-GENE-1013248
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 962
• Identity: 248/962 - (25%)
• Similarity: 373/962 - (38%)
• Gaps: 261/962 - (27%)

  Fly   759 QNGQTLHAATAAGVDKQQQ--QLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVS 821
            ||..:.:.::|:|...:.|  |:.|:::|.:        |.:.|:..|...|....|...|||:|
 Frog     7 QNSSSTNGSSASGSSTRPQISQMSLYERQAV--------QALQALHRQPNAAQYFHQLMLQQQLS 63

  Fly   822 QQQ--QVNAQQQQAVAQQQQAVA----QAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQ 880
            ..|  .:.|.||..:|..:||.:    .|||....|..|...:.:...|.|:. ||.:  .||:.
 Frog    64 NAQLHSLAAVQQATIAASRQAASPNTGSAQQTNTTQGSQANLSTSSSAQLLSR-TQNV--TAPSA 125

  Fly   881 FITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQ------------ 933
                          ..|.|..|...|.:....|.|.|...:|   .|..|::|
 Frog   126 --------------TTLTQSVLLSNASSPPLGQSQTQMYLRQ---PQLGNLLQVNRSLGRGVPLN 173

  Fly   934 -QIVVQQSGATSQQ---TSQQQQ--HHQSGQLQLSSVPFSVSSSTT---------PAGIATSSAL 983
             |:::..:|:.:.|   ||.|.|  |..|.|:|..:|....:::||         ||.:||...:
 Frog   174 SQLILMPNGSVAVQQEVTSPQNQGVHQDSDQVQNLAVRGQQTAATTSAAGATISQPAPLATKPQI 238

  Fly   984 QAALSA------SGAIFQTAK------PGTCSSSSPT-------------SSVVTITNQSSTP-- 1021
            ..|.||      |..:.|:.|      .||.|..|.|             .||.....:::||
 Frog   239 HPASSAAPTQIPSPNVPQSVKNPVGSTGGTVSQGSQTEAEGRKADGEGVQQSVGINLTRAATPAP 303

  Fly  1022 ---LVTSSTVASI------QQAQT---QSAQVHQHQ--QLISATI-------AGGTQQQPQGPPS 1065
               |::|:|...|      ||.|.   |...:|||:  ||:.|:.       ...|||..|
 Frog   304 NQTLISSATYTHIQPHSVLQQKQVVFQQQIAIHQHRQSQLLHASTHLQLAQPQAATQQGLQ---- 364

  Fly  1066 LTPTTNPILAMTSMMNAT-VGHLSTAPPVTVSVTSTAVTSSPGQLV-------LLSTASSGGGGS 1122
             ||.|...|.:..|:.|| ...:.|..||.:.      ...||:.|       .|...:|.|...
 Frog   365 -TPGTQQTLVVQPMLQATSESAIPTKAPVPIQ------PKQPGKGVPPLNLQGHLGAKASQGTRP 422

  Fly  1123 IPATPTKETP----------SKGPTATLVPIGSPKTP--VSGKDTCTTPKSSTPATVSASVEASS 1175
            :| .|:...|          .:||...|. :|:.:.|  .|.....|.|.|  ||.|::.|..:.
 Frog   423 LP-IPSPSQPHIPVQLVGARQQGPAQALA-LGATQVPSQASSMTQLTLPPS--PAPVASVVAGAV 483

  Fly  1176 STGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATST 1240
            ...:|...|....:.|.|.|........:.:.:|.|..::.|.......|             .|
 Frog   484 QESQAGFYGVLQGKLSGPGKRKAEVEDDRDDPSVLPVKASPPTDAPPTVE-------------ET 535

  Fly  1241 STTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNV 1305
            ||...        :..|:|.||...|        :.:.||....:.||..:.....|:|::||.:
 Frog   536 STPAD--------KPEAATQVSPTLT--------VLAPTSVPALSISSRQHSDSKPPQAIVKPQI 584

  Fly  1306 LTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAP------------ 1358
            |||:|:||:|||..|||||     ....:..||.|:.|:  :.:.|....|.|
 Frog   585 LTHIIEGFVIQEGAEPFPV-----GSPQLLKEPEKQAAS--DTVLLPPAESPPPQAVGDTAASDS 642

  Fly  1359 -GSDMVACEQCGKMEHKAKLK-RKRYCSPGCSR--------------------QAKNGIGGVGSG 1401
             .|.::.||.|||.....:.: .||:||..|::                    |...|:.....|
 Frog   643 GSSKLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRKKLKELQEAGGVRARRRG 707

  Fly  1402 ---ETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAA 1463
               .::.:....|.|           :.|.|:..:........|:|   ..::..||
 Frog   708 PRRNSSEIARAKIQG-----------KRMREDSSRGSDNSSYDEAF---SPNSPAPP-------- 750

  Fly  1464 ISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPPISS----WSVDDVSNFIRE 1524
             |..:|.....||               |....|.:|::.|.:...:||    |||::|..||..
 Frog   751 -SCRTPHGDRDGS---------------TPTGGPSNSDLLGINPMFLSSNPSRWSVEEVYEFISS 799

  Fly  1525 LPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKE 1576
            |.||||..:||..|||||||||||||:||::|:.:||||||||.||:..:||
 Frog   800 LQGCQDLAEDFRSQEIDGQALLLLKEEHLMSALNIKLGPALKICAKINLLKE 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-p	NP_476871.2	DUF5585	1015..>1232	CDD:465521	61/259 (24%)
		SAM_Ph1,2,3	1508..1576	CDD:188976	41/71 (58%)
phc1	XP_031761253.1	PHA03247	<381..631	CDD:223021	71/295 (24%)
		PHC2_SAM_assoc	678..783	CDD:465202	19/142 (13%)
		SAM_Ph1,2,3	783..851	CDD:188976	40/67 (60%)