Protein Alignment Unc-76 and fez1

DIOPT Version :9

• Sequence 1: NP_001259172.1
• Gene: Unc-76 / 31179
• FlyBaseID: FBgn0040395
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001072905.1
• Gene: fez1 / 780367
• XenbaseID: XB-GENE-945356
• Length: 392
• Species: Xenopus tropicalis
• Alignment Length: 416
• Identity: 122/416 - (29%)
• Similarity: 185/416 - (44%)
• Gaps: 123/416 - (29%)

  Fly   122 LEKRSLAVGDHVDNFTETFGG--SLEDLVNTFDEKITKCFGNYEENVEELAPV----QVRSQEEI 180
            :|..||:   .::||:.....  |:|||||.||||:..||.||....|.||||    |::.:||.
 Frog    37 IEDASLS---ELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEER 98

  Fly   181 MNECQMWWTITGNFGNILPIDWSKSYTRQMHMPTLNLGQNHTKQQQQNRNQQQQLHNQSHQAYPH 245
            :.:.::|..:|.|:..:....|     |...:.:||           ......:.|.:..
 Frog    99 LRDEEVWDALTDNYIPLTGETW-----RDQSLESLN-----------GNMSDSEFHEKDE----- 142

  Fly   246 TNGLGSGSGSGLDAQTPGDEFNDLTSEDEAVANDLDMHALILNGLNGDMDDQPIKTVEEVIKEID 310
                              :|.|:.:..|..:.                  ::|:.|.::||:||:
 Frog   143 ------------------EELNEKSENDSGII------------------EEPLITADQVIEEIE 171

  Fly   311 DIM----DEAESPLDEPETCDSEVIEKAREVLGAPLYA------------EKLQYLTTTQLNELY 359
            ::|    |..|..||:.:.....:...:..||...:.|            ..||::|:.:|:||.
 Frog   172 EMMQNSPDPEEEDLDDEDHDTENISSHSDSVLLQEMQALSQNFNNNWSTEAGLQHMTSMELSELL 236

  Fly   360 MEMEVLIQELSETLINELALRDELEFEKELKNSFISLLLAVQNKRRQYH--VEKKR--------- 413
            ..:|..|.:.||.|:.:||.|||||||||:|||||:.|:.||||::::.  |:|||
 Frog   237 DRVERAICDYSEELVQQLARRDELEFEKEVKNSFITALIEVQNKQKEHRELVKKKRKDKGMSLHI 301

  Fly   414 ------GKF------------------------QGPEPKYLTTVIPYHLENGTPNNQSLQVLIKI 448
                  |:.                        .|.:.:||.|||||......|:.:.||:|..|
 Frog   302 SRAENNGQMPMKRFSIEGLSNILQSGIRQTFGNSGNDKQYLNTVIPYEKRGTPPSVEDLQMLTNI 366

  Fly   449 LKAINEDSPTVPALLTDYILKVLCPT 474
            |.|:.|||..||.|||||||||||||
 Frog   367 LYAMKEDSEKVPMLLTDYILKVLCPT 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-76	NP_001259172.1	FEZ	143..418	CDD:285060	84/335 (25%)
fez1	NP_001072905.1	FEZ	57..297	CDD:311622	83/296 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3601
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3359
OMA	1	1.010	-	-		QHG46356
OrthoDB	1	1.010	-	-		D1186463at2759
OrthoFinder	1	1.000	-	-		FOG0002964
OrthoInspector	1	1.000	-	-		otm47738
Panther	1	1.100	-	-	O	PTHR12394
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1959
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080