Protein Alignment Unc-76 and fez2

DIOPT Version :9

• Sequence 1: NP_001259172.1
• Gene: Unc-76 / 31179
• FlyBaseID: FBgn0040395
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_017949372.1
• Gene: fez2 / 549098
• XenbaseID: XB-GENE-951431
• Length: 408
• Species: Xenopus tropicalis
• Alignment Length: 517
• Identity: 165/517 - (31%)
• Similarity: 253/517 - (48%)
• Gaps: 168/517 - (32%)

  Fly    15 APLAKFEETDEWGGCDFI------SSQNAINDTLNLNLKDSSAGGKPDATKLRLLEDAVRDAHVS 73
            ||||:|:|  :|.  ||.      ||.:...|.:|.|...:.|
 Frog     3 APLAQFDE--DWQ--DFYEFRAASSSDSGCLDKVNSNTPSAVA---------------------- 41

  Fly    74 KNGGGVVGGGAGSISPNCNTLQGGSLIEIGLSDVGLVPGEGAGVGLDGLEKRSLAVGDHVDN-FT 137
                .::|.|||::              :.|.|:.                       .:|| |:
 Frog    42 ----PLLGQGAGAV--------------VALEDLA-----------------------ELDNGFS 65

  Fly   138 -ETFGG--SLEDLVNTFDEKITKCFGNYEENVEELAPVQVRSQEEIMNECQMWWTITGNFGNILP 199
             |..||  |:|||||.||||::.||.||..:...:|||:..::|.:|.:.::|..:|.|:||::|
 Frog    66 MEIMGGFKSMEDLVNEFDEKLSVCFRNYSTDTGTIAPVRPITEEGMMKDDEIWNALTDNYGNVMP 130

  Fly   200 IDWSKSYTRQMHMPTLNLGQNHTKQQQQNRNQQQQLHNQSHQAYPHTNGLGSGSGSGLDAQTPGD 264
            :||..|:.|.:|:|||||   ..|...:|.|                          ||
 Frog   131 VDWKTSHARALHLPTLNL---LDKAVNENLN--------------------------LD------ 160

  Fly   265 EFNDLTSEDEAVANDLDMHALILNGLNGDMDDQPIKTVEEVIKEIDDIMDEAESPLDEPETCD-- 327
                 .|:||.:...||||::|::.:|    ::|:.|.|:||:||:::|.|:..|.::...|.
 Frog   161 -----LSDDEELREQLDMHSIIVSCIN----EEPLFTAEQVIEEIEEMMQESPDPEEDDTHCQSD 216

  Fly   328 -----SEVIEKAREVLGAPLYAEKLQYLTTTQLNELYMEMEVLIQELSETLINELALRDELEFEK 387
                 |:.|:..::......:.:|::.::..:||:|..|:|..|::.||.||.:|||||||||||
 Frog   217 RLSMLSQEIQTLKKASTNRSHEDKVKMMSVAELNDLLEEIETAIKDYSEELIQQLALRDELEFEK 281

  Fly   388 ELKNSFISLLLAVQNKRRQY--HVEKKR--------------------------------GKFQ- 417
            |:||||||:|:.||||::::  :|:|||                                ..|:
 Frog   282 EVKNSFISVLIEVQNKQKEHKENVKKKRRVKSANAQNGTKERSHMPGTRFSMEGLSNVIQNSFRQ 346

  Fly   418 -----GPEPKYLTTVIPYHLENGTPNNQSLQVLIKILKAINEDSPTVPALLTDYILKVLCPT 474
                 |.|.:||||||||..:||.|:.:.||:|.|||:|:.:||..||:|||||||||||||
 Frog   347 TFGNPGGEKQYLTTVIPYEEKNGPPSIEDLQILTKILRAMKDDSDKVPSLLTDYILKVLCPT 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-76	NP_001259172.1	FEZ	143..418	CDD:285060	101/321 (31%)
fez2	XP_017949372.1	FEZ	74..313	CDD:369503	100/282 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I3601
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3742
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3359
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1186463at2759
OrthoFinder	1	1.000	-	-		FOG0002964
OrthoInspector	1	1.000	-	-		otm47738
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1959
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060