Protein Alignment Unc-76 and unc-76

DIOPT Version :9

• Sequence 1: NP_001259172.1
• Gene: Unc-76 / 31179
• FlyBaseID: FBgn0040395
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001256645.1
• Gene: unc-76 / 180014
• WormBaseID: WBGene00006808
• Length: 388
• Species: Caenorhabditis elegans
• Alignment Length: 398
• Identity: 139/398 - (34%)
• Similarity: 207/398 - (52%)
• Gaps: 95/398 - (23%)

  Fly   123 EKRSLAVGDHVDNFTETFGGSLEDLVNTFDEKITKCFGNYEENVEELAPVQVRSQEEIMNECQMW 187
            ||.........:...:.|.|||||||..|||||..|..::|....::||||:|:|||:|||.|.|
 Worm    34 EKHHCNSNSDEERLHDEFSGSLEDLVGNFDEKIAACLKDHEVTTADIAPVQIRTQEEVMNESQTW 98

  Fly   188 WTITGNFGNILPIDWSKSYTRQMHMPTLNLGQNHTKQQQQNRNQQQQLHNQSHQAYPHTNGLGSG 252
            ||:|||||||.|:|:.                                          |:.:...
 Worm    99 WTLTGNFGNIQPLDFG------------------------------------------TSSICKK 121

  Fly   253 SGSGLDAQTPGDEFN---DLTSED--EAVANDLDMHALILNGLNGDMD---DQPIKTVEEVIKEI 309
            ..:.||:.:..|:.:   .:|:.|  :.:...:|:|.:| ...:|..|   :.|.:|.::||:||
 Worm   122 MAAALDSDSLKDDASTRRSMTNSDDEDLLRQQMDVHQMI-GHHHGSTDTGGETPPQTADQVIEEI 185

  Fly   310 DDIM------------------DEAESPLDEP-----ETCDSEV-IEKAREVLGAPLYAEK---- 346
            |:::                  |...|.:..|     ::.|::: :..|:.::..|..|.|
 Worm   186 DEMLQSCDFTGSMMTDRTMESVDSMYSSMRSPFPSSIQSSDADIKLRSAQALVSNPDTAAKTAAF 250

  Fly   347 ---LQYLTTTQLNELYMEMEVLIQELSETLINELALRDELEFEKELKNSFISLLLAVQNKRRQYH 408
               ||.|:.::|..|..|||.||:..:|:|::|||.||||::|||:||||||||||:|||||.|.
 Worm   251 HSDLQELSYSKLVTLCAEMEQLIRVYNESLVDELAHRDELDYEKEMKNSFISLLLAIQNKRRVYA 315

  Fly   409 VEKKR--GKFQGPE--PKYLTTVIPY----HLENGTPNNQSLQVLIKILKAINEDSPTVPALLTD 465
            .::||  ||.....  |:|||..|||    |::|.     |:..|||||:||::|:.|||.||||
 Worm   316 NDRKRKVGKASDASQLPQYLTATIPYNDHQHIDNA-----SIASLIKILRAIHDDNTTVPTLLTD 375

  Fly   466 YILKVLCP 473
            |||..:||
 Worm   376 YILTHVCP 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Unc-76	NP_001259172.1	FEZ	143..418	CDD:285060	105/315 (33%)
unc-76	NP_001256645.1	FEZ	54..326	CDD:285060	105/314 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157415
Domainoid	1	1.000	156	1.000	Domainoid score	I2578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3742
Inparanoid	1	1.050	208	1.000	Inparanoid score	I2402
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46356
OrthoDB	1	1.010	-	-		D1186463at2759
OrthoFinder	1	1.000	-	-		FOG0002964
OrthoInspector	1	1.000	-	-		oto17670
orthoMCL	1	0.900	-	-		OOG6_106736
Panther	1	1.100	-	-	LDO	PTHR12394
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3073
SonicParanoid	1	1.000	-	-		X1959
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940