DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16903 and ccnl2

DIOPT Version :9

Sequence 1:	NP_569980.1	Gene:	CG16903 / 31178	FlyBaseID:	FBgn0040394	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	XP_012822126.1	Gene:	ccnl2 / 595011	XenbaseID:	XB-GENE-956522	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	506	Identity:	231/506 - (45%)
Similarity:	306/506 - (60%)	Gaps:	93/506 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 RLFNRIVLTLENSLIPEGKIDVTPSSQDGLDHETEKDLRILGCELIQTAGILLRLPQVAMATGQV 141
            :|::.::::|||.|:.|.:..:|||..||:|..||.|||.:||||:|.|||||||||||||||||
Frog    23 KLYSGVMISLENCLMAEERCALTPSVVDGIDVNTEIDLRCVGCELVQAAGILLRLPQVAMATGQV 87

  Fly   142 LFQRFFYSKSFVRHNMETVAMSCVCLASKIEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYY 206
            |||||||:||||:|:||.|||:||.||||||||||||||||||||.::|:|.:::.:|::||..|
Frog    88 LFQRFFYTKSFVKHSMEHVAMACVHLASKIEEAPRRIRDVINVFHRLRQLREKQKSTPLILDQEY 152

  Fly   207 TNLKMQVIKAERRVLKELGFCVHVKHPHKLIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMR 271
            .|||.|:||||||||||||||||||||||:||||||||:.|:::.|:|.|||:||||||||||:|
Frog   153 VNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNKHLVQTSWNYMNDSLRTDVFVR 217

  Fly   272 YTPEAIACACIYLSARKLNIPLPNSPPWFGIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVD 336
            :.||.||||||:|:||.|.|||||.|.||.:|.....||.:||.:::.||.|.|..|..||..|:
Frog   218 FNPETIACACIFLAARTLEIPLPNRPHWFYLFGASEEDIKEICLQILRLYTRKKADVALLENKVE 282

  Fly   337 ELKKRYIDARNKTK----------------------------EANTP-PAVITVDRN-----NGS 367
            :.|....:|:.|.|                            :||.| |..:...:|     :|:
Frog   283 KRKLFIEEAKAKAKGLLPDGTPRLENAPEFSPSLKNDSPKELKANKPSPLAVHALKNCKRKVDGT 347

  Fly   368 HNAWGGFIQRAIPLPLPSEKSP------QKDSRSRSRSRTRTHSRT-PRSRSPRSRSPSRERTKK 425
            ..              |:..||      .:||||.||||.:::||: .||:||:.|.........
Frog   348 KR--------------PTSSSPVNGVSKGRDSRSGSRSRDQSYSRSQSRSQSPKRRKSQSYSPSS 398

  Fly   426 THRSRS-SRSRSRSPPKHK--------------------KKSRHYSRSPTRSNSP-HSKHRKSKS 468
            ..:||| |||||.||| ||                    |...|..||.:||:|| ||:.|:|..
Frog   399 DSKSRSPSRSRSDSPP-HKPNHGSYKSTKGHVYGNNSDYKYQGHKRRSRSRSSSPSHSRSRESSD 462

  Fly   469 S--RERSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKHSRYSSSSSRR 517
            |  .::.::|.:::||             :..:.||:.|....|...|..|
Frog   463 SGKYKKKDHYYRRERS-------------RSYDRVSHRGYDREYHGHSHHR 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16903	NP_569980.1	CYCLIN	114..203	CDD:238003	66/88 (75%)
CG16903	NP_569980.1	CYCLIN	235..321	CDD:214641	51/85 (60%)
ccnl2	XP_012822126.1	CYCLIN	60..133	CDD:238003	62/72 (86%)
ccnl2	XP_012822126.1	CYCLIN	183..265	CDD:214641	50/81 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3440
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	389	1.000	Inparanoid score	I1957
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002258
OrthoInspector	1	1.000	-	-		otm48266
Panther	1	1.100	-	-	O	PTHR10026
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1832
SonicParanoid	1	1.000	-	-		X1491
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090