DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16903 and Ccnl1

DIOPT Version :9

Sequence 1:	NP_569980.1	Gene:	CG16903 / 31178	FlyBaseID:	FBgn0040394	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_064321.2	Gene:	Ccnl1 / 56706	MGIID:	1922664	Length:	532	Species:	Mus musculus

Alignment Length:	554	Identity:	258/554 - (46%)
Similarity:	325/554 - (58%)	Gaps:	75/554 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 HSNSVNISNNNSSSGAAPGADAAGGDAGGVAAAQADANKPIY--PRLFNRIVLTLENSLIPEGKI 96
            |..|...:...:::.|:..|.:|||.:.|...........|.  .||::.:.||:::|||||.::
Mouse     6 HPTSTAAAAAAAAASASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERL 70

  Fly    97 DVTPSSQDGLDHETEKDLRILGCELIQTAGILLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVA 161
            ..|||.|||||..:|.|||||||||||.|||||||||||||||||||.|||||||||:|:.|.||
Mouse    71 SPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVA 135

  Fly   162 MSCVCLASKIEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYYTNLKMQVIKAERRVLKELGF 226
            |:|:.|||||||||||||||||||||::|:|.::..||::||..|.|.|.|||||||||||||||
Mouse   136 MACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGF 200

  Fly   227 CVHVKHPHKLIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMRYTPEAIACACIYLSARKLNI 291
            |||||||||:||||||||:.|:::.|:|.:||:|||||||:||:|:.||.||||||||:||.|.|
Mouse   201 CVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQI 265

  Fly   292 PLPNSPPWFGIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVDELKKRYIDARNKTKEANT-- 354
            |||..|.||.:|.....:|.:||...:.||.|.||..|.||..|::.|....:|:.|.|..|.
Mouse   266 PLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNLDG 330

  Fly   355 PPAVITVDRNNGSHNAWGGFIQRAIPLPLPS--------EKSP---------------------- 389
            .||:.|:          |||    .|...||        ||||
Mouse   331 TPALSTL----------GGF----SPASKPSSPREVKAEEKSPVSINVKTVKKEPEDRQQASKSP 381

  Fly   390 ----QKDS-RSR-SRSRTRTHSRTPRSRSPRSRSPSRERTKKTHRSRSSRSRSRSPPKHKKKSRH 448
                :||| ||| |||.:|:.||| |||| ||.||.|....:..||.:..|||||      :||.
Mouse   382 YNGVRKDSKRSRTSRSASRSRSRT-RSRS-RSHSPRRHYNNRRSRSGTYSSRSRS------RSRS 438

  Fly   449 YSRSPTRSNSPHSKHRKSKSSRE------RSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKH 507
            :|.||.|.::..|.|.|:|.:||      |..:..||.||.:...:.:..|       |:...:|
Mouse   439 HSESPRRHHNHGSPHLKAKHTREDLKSSNRHGHKRKKSRSRSQSKTRDHSD-------VTKKHRH 496

  Fly   508 SRYSSSSSRRNSGGGGDGRSGGGGGGGGGGNGNH 541
            .|......|..|........|...||...|:|.|
Mouse   497 ERGHHRDRRERSRSFERSHKGKHHGGSRSGHGRH 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16903	NP_569980.1	CYCLIN	114..203	CDD:238003	69/88 (78%)
CG16903	NP_569980.1	CYCLIN	235..321	CDD:214641	48/85 (56%)
Ccnl1	NP_064321.2	CYCLIN	88..160	CDD:238003	62/71 (87%)
		Cyclin-like 1	94..196		77/101 (76%)
		Cyclin-like 2	209..293		48/83 (58%)
		CYCLIN	211..280	CDD:214641	44/68 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	332..532		71/228 (31%)
		RS	396..438		23/49 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3371
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	415	1.000	Inparanoid score	I1812
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002258
OrthoInspector	1	1.000	-	-		otm43133
orthoMCL	1	0.900	-	-		OOG6_102010
Panther	1	1.100	-	-	LDO	PTHR10026
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1832
SonicParanoid	1	1.000	-	-		X1491
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.850