DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16903 and ccnt2b

DIOPT Version :9

Sequence 1:	NP_569980.1	Gene:	CG16903 / 31178	FlyBaseID:	FBgn0040394	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_997751.1	Gene:	ccnt2b / 321464	ZFINID:	ZDB-GENE-030131-183	Length:	569	Species:	Danio rerio

Alignment Length:	550	Identity:	115/550 - (20%)
Similarity:	218/550 - (39%)	Gaps:	103/550 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 VAAAQADANKPIYPRLFNRIVLTLENSLIPEGKIDVTPSSQDGLDHETEKDLRILGCELIQTAGI 127
            :||.|..::|.::.|                .:.:.|||.:.|::.:.|...|.....|||..|.
Zfish     2 MAAVQRGSSKWLFTR----------------EQFENTPSRRCGVEPDRELSYRQQAANLIQDMGQ 50

  Fly   128 LLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVAMSCVCLASKIEEAPRRIRDVINVFHHIKQVR 192
            .|.:.|:.:.|..|...||:...||.:.:...::.:.:.||:|:||.||::..||.|.|
Zfish    51 RLNVSQLTINTAIVYMHRFYMLNSFTKFHRNIISPTTLFLAAKVEEQPRKLEHVIKVAH------ 109

  Fly   193 AQKEISPMVLDPY----------YTNLKMQVIKAERRVLKELGFCVHVKHPHKLIVMYLQVLQYE 247
                   ..|:|:          |.....:::..|..||:.|||.:.::|||..:|...|:::..
Zfish   110 -------ACLNPHDPPLDSKSSAYLQQAQELVLLETIVLQTLGFEITIEHPHTDVVRCTQLVRAS 167

  Fly   248 KHEKLMQLSWNFMNDSLRTDVF-MRYTPEAIACACIYLSARKLNIPLPNSPP----WFGIFR-VP 306
            |  .|.|.|:....:||....| :::.|..:||.||:|:.:..|..:|.|..    |..:.| |.
Zfish   168 K--DLAQTSYFMATNSLHLTTFCLQHKPTVVACVCIHLACKWSNWEIPVSSDGKHWWEYVDRAVT 230

  Fly   307 MADITDICYRVMELYMRSKPVVEKLE-------AAVDELKKRYIDARNKTKEANT---------- 354
            :..:.|:.:..:::..::...::::.       |...:|..:.:|...::...:|
Zfish   231 LQLLDDLTHEFLQILEKTPSRLKRIRNWRATQAAKKPKLDNQSLDGSFQSLNQDTSLMSSMCDLG 295

  Fly   355 ------PPAVITVDRNNGSHNAWGGFIQRAIPLPLPSEKSPQKDSRSRSRSRTRTHSRTPRSRSP 413
                  |.....:|.::.|.|........|...|.|..::... ..:...:.|..|..:..:.:|
Zfish   296 AGMYSDPSTSFPLDGSSLSLNGLSNLQSSAFGFPAPISQTADA-FLALQAAPTSKHGHSSATLAP 359

  Fly   414 RSRSPSRERTKKTHRSRSSRSRSRSPPKHKKKSRHYSRSPTRS-----NSPHSKHRKSKS-SRER 472
            :..:..:.|.|:|...:..|.......:|:|.. |.:..|:.|     |......|.||| |.:|
Zfish   360 QKLTLEKYREKQTELEQRRRHEEEDGDQHRKHG-HLTSEPSTSIRLKYNQQQVLERPSKSGSLKR 423

  Fly   473 SEYYSKKDRSGNPG--------SSNNLGDGDKYRNSVSNSGKHSRYSSSSSRRNSGGGGDGRSGG 529
            ....|.::.|.:..        ||::.|......:.:|:..||..:||..:.|:.
Zfish   424 RHPSSSENGSASQEELKMKIKVSSDSSGSSKSRHSPLSSREKHREHSSHKTARHD---------- 478

  Fly   530 GGGGGGGGNGNHGSRGGHKHRDGDRSRDRK 559
                   .:.:|||...|.|.....|:..:
Zfish   479 -------SSHSHGSHHHHHHHHHHSSKSHR 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16903	NP_569980.1	CYCLIN	114..203	CDD:238003	24/88 (27%)
CG16903	NP_569980.1	CYCLIN	235..321	CDD:214641	22/91 (24%)
ccnt2b	NP_997751.1	Cyclin_N	13..149	CDD:278560	39/164 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1437076at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820