DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16903 and Ccnl2

DIOPT Version :9

Sequence 1:	NP_569980.1	Gene:	CG16903 / 31178	FlyBaseID:	FBgn0040394	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	XP_006239606.1	Gene:	Ccnl2 / 298686	RGDID:	1309149	Length:	521	Species:	Rattus norvegicus

Alignment Length:	566	Identity:	250/566 - (44%)
Similarity:	327/566 - (57%)	Gaps:	99/566 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SSSGA----APGADAAGGDAGGVAAAQADANKPIYPRLFNRIVLTLENSLIPEGKIDVTPSSQDG 105
            :::||    ||...|....:||  ||.......|..||::.:::||||.|:|:.|:..|||...|
  Rat     4 AAAGASGLMAPALAACSSGSGG--AAPGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSG 66

  Fly   106 LDHETEKDLRILGCELIQTAGILLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVAMSCVCLASK 170
            ||.:||..||::||||||.||||||||||||||||||||||||:||||:|:||.|:|:||.||||
  Rat    67 LDIDTETGLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASK 131

  Fly   171 IEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYYTNLKMQVIKAERRVLKELGFCVHVKHPHK 235
            ||||||||||||||||.::.:|.:|:..|:|||..|.|||.|:||||||||||||||||||||||
  Rat   132 IEEAPRRIRDVINVFHRLRHLREKKKPVPLVLDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHK 196

  Fly   236 LIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMRYTPEAIACACIYLSARKLNIPLPNSPPWF 300
            :||||||||:.|:::.|:|.:||:||||||||||:|:.||:||||||||:||.|.|||||.|.||
  Rat   197 IIVMYLQVLECERNQHLVQTAWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWF 261

  Fly   301 GIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVDELKKRYIDARNKTKEANTPPAVITVDRNN 365
            .:|.....:|.:||:::::||.|.|..:..||:.|::.|....:|:.:.|....|.:...:|
  Rat   262 LLFGATEEEIQEICFKILQLYTRKKVDLTHLESEVEKRKHAIEEAKARAKGLLPPGSAPGLD--- 323

  Fly   366 GSHNAWGGFIQRAIPLPLPSE------------------KSPQK--------------DSRSRSR 398
               :|..||.....|:..|.|                  :.|:|              :|||:||
  Rat   324 ---SATAGFSPAPKPVESPKEGKGSKSSPLSVKNAKRKMEGPKKAKGDSPVNGLLKGQESRSQSR 385

  Fly   399 SRTRTHSRTP-RSRSPRSRSPSRERTKKTHRSRS-SRSRSRSPPKHKKKSRHYSRSPTR------ 455
            ||.:::||:| ||.||:.|......|....:|:| |||||.|||:...:...|..|..|
  Rat   386 SREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQVHRGAPYKGSEVRGSRKSK 450

  Fly   456 -----SNSPHSKHRKSKSSRERSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKHSRYSSSSS 515
                 :..|| |.|...|||.||....:.|.||            ||:       |.|.|.....
  Rat   451 DCKHLTQKPH-KSRSRSSSRSRSRSRERTDSSG------------KYK-------KKSHYYRDQR 495

  Fly   516 RRNSGGGGDGRSGGGGGGGGGGNGNHGSRGGHKH-RD-GDRSRDRK 559
            |..|      ||              ..|.||:: || ...||.|:
  Rat   496 RERS------RS--------------YERTGHRYERDHPGHSRHRR 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16903	NP_569980.1	CYCLIN	114..203	CDD:238003	67/88 (76%)
CG16903	NP_569980.1	CYCLIN	235..321	CDD:214641	50/85 (59%)
Ccnl2	XP_006239606.1	CYCLIN_CCNL2_rpt1	33..188	CDD:410293	104/154 (68%)
Ccnl2	XP_006239606.1	CYCLIN_CCNL2_rpt2	193..315	CDD:410296	63/121 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3297
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	412	1.000	Inparanoid score	I1795
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002258
OrthoInspector	1	1.000	-	-		otm45201
orthoMCL	1	0.900	-	-		OOG6_102010
Panther	1	1.100	-	-	O	PTHR10026
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1491
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.820