DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4045 and Mettl1

DIOPT Version :9

Sequence 1:	NP_569978.1	Gene:	CG4045 / 31176	FlyBaseID:	FBgn0025629	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_003750377.1	Gene:	Mettl1 / 679091	RGDID:	1593036	Length:	267	Species:	Rattus norvegicus

Alignment Length:	246	Identity:	147/246 - (59%)
Similarity:	178/246 - (72%)	Gaps:	21/246 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PQKRYYRQRAHSNPIADHSFDYPARPEDVDWRSMYPGI-------------------QQGQQVSF 75
            ||||||||||||||:|||:..||.:||::||..:||..                   ..|.||.|
  Rat     9 PQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPPNQNKSHDDPKDEKEKHSGAQVEF 73

  Fly    76 ADIGCGYGGFLVTLGEMFPEKLSIGMEIRVKVSDYVVDRIAALRRRCADTGAYQNIACLRTNAMK 140
            |||||||||.||.|..:||:.|.:|:||||||||||.|||.||  |....|.:|||||||:||||
  Rat    74 ADIGCGYGGLLVALSPLFPDTLILGLEIRVKVSDYVQDRIRAL--RATPGGGFQNIACLRSNAMK 136

  Fly   141 YLPNYFVKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYILRKGGLLYTMTDVEDLHKWIV 205
            :|||:|.||||.|||||:|||||||.|||||||:..||:||||:||.|||:||:|||.:||:|:.
  Rat   137 HLPNFFRKGQLAKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTITDVLELHEWMC 201

  Fly   206 THMEEHPLYERLTEEEANADPITPKLYQSSEEGAKVVRNKGDHFLAIFRRL 256
            ||.|||||:|.:..||.:.||:...|..|:|||.||:||.|.:|.|||||:
  Rat   202 THFEEHPLFEHVPLEELSEDPVVEHLGTSTEEGKKVLRNNGKNFPAIFRRI 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4045	NP_569978.1	Methyltransf_4	71..251	CDD:280538	116/179 (65%)
Mettl1	XP_003750377.1	TrmB	9..251	CDD:223298	145/243 (60%)
Mettl1	XP_003750377.1	Methyltransf_4	70..247	CDD:280538	116/178 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352708
Domainoid	1	1.000	245	1.000	Domainoid score	I2124
eggNOG	1	0.900	-	-		E1_COG0220
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3918
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2566
OMA	1	1.010	-	-		QHG53626
OrthoDB	1	1.010	-	-		D1417652at2759
OrthoFinder	1	1.000	-	-		FOG0002765
OrthoInspector	1	1.000	-	-		oto96951
orthoMCL	1	0.900	-	-		OOG6_100919
Panther	1	1.100	-	-	LDO	PTHR23417
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2148
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810