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Protein Alignment CG4045 and METTL1

DIOPT Version :9

Sequence 1:	NP_569978.1	Gene:	CG4045 / 31176	FlyBaseID:	FBgn0025629	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_005362.3	Gene:	METTL1 / 4234	HGNCID:	7030	Length:	276	Species:	Homo sapiens

Alignment Length:	255	Identity:	151/255 - (59%)
Similarity:	183/255 - (71%)	Gaps:	21/255 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NPTSAVTGLPQKRYYRQRAHSNPIADHSFDYPARPEDVDWRSMYP----GIQQGQ---------- 71
            |...|....||||||||||||||:|||:..||.:||::||..:||    .:.|.|
Human     7 NVAGAEAPPPQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPLTQNQSHDDPKDKKE 71

  Fly    72 -----QVSFADIGCGYGGFLVTLGEMFPEKLSIGMEIRVKVSDYVVDRIAALRRRCADTGAYQNI 131
                 ||.||||||||||.||.|..:||:.|.:|:||||||||||.|||.||  |.|..|.:|||
Human    72 KRAQAQVEFADIGCGYGGLLVELSPLFPDTLILGLEIRVKVSDYVQDRIRAL--RAAPAGGFQNI 134

  Fly   132 ACLRTNAMKYLPNYFVKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYILRKGGLLYTMTD 196
            ||||:||||:|||:|.||||.|||||:|||||||.|||||||:..||:||||:||.|||:||:||
Human   135 ACLRSNAMKHLPNFFYKGQLTKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTITD 199

  Fly   197 VEDLHKWIVTHMEEHPLYERLTEEEANADPITPKLYQSSEEGAKVVRNKGDHFLAIFRRL 256
            |.:||.|:.||.|||||:||:..|:.:.||:...|..|:|||.||:||.|.:|.|||||:
Human   200 VLELHDWMCTHFEEHPLFERVPLEDLSEDPVVGHLGTSTEEGKKVLRNGGKNFPAIFRRI 259

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.