DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4045 and Mettl1

DIOPT Version :9

Sequence 1:	NP_569978.1	Gene:	CG4045 / 31176	FlyBaseID:	FBgn0025629	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	XP_006513375.1	Gene:	Mettl1 / 17299	MGIID:	1339986	Length:	315	Species:	Mus musculus

Alignment Length:	246	Identity:	149/246 - (60%)
Similarity:	180/246 - (73%)	Gaps:	21/246 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PQKRYYRQRAHSNPIADHSFDYPARPEDVDWRSMYPGI-------------------QQGQQVSF 75
            ||||||||||||||:|||:..||.:||::||..:||..                   ..|.||.|
Mouse    57 PQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPLIQNKSHDDPKDEKEKHSGAQVEF 121

  Fly    76 ADIGCGYGGFLVTLGEMFPEKLSIGMEIRVKVSDYVVDRIAALRRRCADTGAYQNIACLRTNAMK 140
            |||||||||.||.|..:||:.|.:|:||||||||||.|||.||  |.|..|.:|||||||:||||
Mouse   122 ADIGCGYGGLLVALSPLFPDTLILGLEIRVKVSDYVQDRIRAL--RAAPGGGFQNIACLRSNAMK 184

  Fly   141 YLPNYFVKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYILRKGGLLYTMTDVEDLHKWIV 205
            :|||:|.||||.|||||:|||||||.|||||||:..||:||||:||.|||:||:|||.:||:|:.
Mouse   185 HLPNFFRKGQLAKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTVTDVPELHEWMC 249

  Fly   206 THMEEHPLYERLTEEEANADPITPKLYQSSEEGAKVVRNKGDHFLAIFRRL 256
            ||.|||||:||:..||.:.|||...|..|:|||.||:||.|.:|.|:|||:
Mouse   250 THFEEHPLFERVPLEELSEDPIVEHLGSSTEEGKKVLRNGGKNFPAVFRRI 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4045	NP_569978.1	Methyltransf_4	71..251	CDD:280538	119/179 (66%)
Mettl1	XP_006513375.1	Methyltransf_4	118..295	CDD:367068	119/178 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849097
Domainoid	1	1.000	248	1.000	Domainoid score	I2127
eggNOG	1	0.900	-	-		E1_COG0220
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3918
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2589
Isobase	1	0.950	-	0	Normalized mean entropy	S384
OMA	1	1.010	-	-		QHG53626
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002765
OrthoInspector	1	1.000	-	-		oto93409
orthoMCL	1	0.900	-	-		OOG6_100919
Panther	1	1.100	-	-	LDO	PTHR23417
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1553
SonicParanoid	1	1.000	-	-		X2148
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740