Protein Alignment Rtca and RTCA

DIOPT Version :10

• Sequence 1: NP_569977.1
• Gene: Rtca / 31175
• FlyBaseID: FBgn0025630
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001124313.1
• Gene: RTCA / 8634
• HGNCID: 17981
• Length: 379
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 140/374 - (37%)
• Similarity: 216/374 - (57%)
• Gaps: 25/374 - (6%)

  Fly     7 LEIDGSYLEGGGQALRNALSLSCILGKPVRVVKIRASRPSPGLSH-------------QHLHGLN 58
            :|:|||.:|||||.||.:.:|||:||.|:||.||||.|.:||||.             |||.||.
Human     6 VEVDGSIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLSSGGWKSKIKVLTRPQHLSGLE 70

  Fly    59 LLRDITNADVVGNYLLSSTVEFTPRTILDNTYRVETHTAASITLIYQMALPVLLFAGRPSRLIVS 123
            ::||:.:..:.|..:.|:.:.|||..|....:..:|.||.|:.|:.|:::|.:|||..||.|.:.
Human    71 MIRDLCDGQLEGAEIGSTEITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSELHLK 135

  Fly   124 GGTNVDFAPPVEYMQEVLLPNLKHFGVSFDLKVQRYGFYPRGQGRCQLDVQPVTKLNSGKLVAFG 188
            ||||.:.||.::|...|..|.::.||..|:..::..|:||:|.|...:.:.||.:||...|...|
Human   136 GGTNAEMAPQIDYTVMVFKPIVEKFGFIFNCDIKTRGYYPKGGGEVIVRMSPVKQLNPINLTERG 200

  Fly   189 RIKSVSGVAYCAGRLPVNIAIDMQQTAQREIHRLWPSQQCSIEPIKHSRQKAFHNGAGILMTVNT 253
            .:..:.|.|:.||.||..:|.||...|.|.|.:.......:|:|::..:.:||.||.||::...|
Human   201 CVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGNGIIIIAET 265

  Fly   254 TSDVVLGASALGKKRIDGHVLGSEASCQLGDYMRKQVCVDDYMQDQLIIYMALAVGRSTMRTGKL 318
            ::..:...|:|||:.::...:|.||:..|...:|....||:|:|||||::||||.|.|.::||.:
Human   266 STGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIVFMALANGVSRIKTGPV 330

  Fly   319 TNHTRTAINVAEQMTGVKF---------DVAMEPGGQMLVSCKGLGHVN 358
            |.||:|||:.|||:...||         |.|.:   ..::.|:|:|..|
Human   331 TLHTQTAIHFAEQIAKAKFIVKKSEDEEDAAKD---TYIIECQGIGMTN 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtca	NP_569977.1	RNA_3prim_cycl	7..338	CDD:274563	134/352 (38%)
RTCA	NP_001124313.1	RNA_3prim_cycl	6..350	CDD:274563	133/343 (39%)