DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and lpd

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_414658.1	Gene:	lpd / 944854	ECOCYCID:	EG10543	Length:	474	Species:	Escherichia coli

Alignment Length:	349	Identity:	78/349 - (22%)
Similarity:	139/349 - (39%)	Gaps:	88/349 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 IVVGGGPSGAVA--------VETIRQEGF--------------TGRLIFVCREDYLPYDRVKISK 225
            :|:|.||:|..|        :||:..|.:              :..|:.|.:.       ::.:|
E. coli    10 VVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKV-------IEEAK 67

  Fly   226 AM----------NLEIEQLRFRDEEFYKEYDI-ELWQGVAAEKLDTAQK--------------EL 265
            |:          ..:|:::|     .:||..| :|..|:|........|              |:
E. coli    68 ALAEHGIVFGEPKTDIDKIR-----TWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEV 127

  Fly   266 HCSNG-YVVKYDKIYLATGCSAFRP-PIPGVNLENVRTVRELADTKAILASITPESRVVCLGSSF 328
            ...|| .|:.:|...:|.|.   || .:|.:..|:.|.   ...|.|:.....|| |::.:|...
E. coli   128 EGENGKTVINFDNAIIAAGS---RPIQLPFIPHEDPRI---WDSTDALELKEVPE-RLLVMGGGI 185

  Fly   329 IALEAAAGLVSKVQSVTVVGRENVPLKAAFGAEIGQRVLQLFE---DNKVVMRMESGIAEIVGNE 390
            |.||......:....:.||...:..:.||     .:.::::|.   ..|..:.:|:.:..:...|
E. coli   186 IGLEMGTVYHALGSQIDVVEMFDQVIPAA-----DKDIVKVFTKRISKKFNLMLETKVTAVEAKE 245

  Fly   391 DGKVSEVVLVDDTRLPC-----DLLILGTGSKLNTQFL--AKSGVKVNRNGSVDVTDFLESNVPD 448
            ||   ..|.::..:.|.     |.:::..|...|.:.|  .|:||:|:..|.:.|...|.:|||.
E. coli   246 DG---IYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQLRTNVPH 307

  Fly   449 VYVGGDIANAHIHGLAHDRVNIGH 472
            ::..|||....:  |||..|:.||
E. coli   308 IFAIGDIVGQPM--LAHKGVHEGH 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	73/340 (21%)
		Pyr_redox	320..402	CDD:278498	16/84 (19%)
		Reductase_C	505..577	CDD:291425
lpd	NP_414658.1	PRK06467	3..472	CDD:180579	78/349 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	1	0.910