DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and TRR2

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_011974.1	Gene:	TRR2 / 856506	SGDID:	S000001148	Length:	342	Species:	Saccharomyces cerevisiae

Alignment Length:	345	Identity:	65/345 - (18%)
Similarity:	124/345 - (35%)	Gaps:	94/345 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 VNNKRLKNMVRRKPDDQRVFIVVGGGPSGAVAVETIRQEGFTGRLIFVCREDYLP--YDRV---- 221
            ::...|..|:..|      ..::|.||:...|.            |::.|.:..|  |:.:
Yeast    16 ISKSVLSRMIHHK------VTIIGSGPAAHTAA------------IYLARAEMKPTLYEGMMANG 62

  Fly   222 -----KISKAMNLE--------------IEQLRFRDEEFYKEYDIELWQGVAAEKLDTAQKELHC 267
                 :::...::|              :|::|.:..:|......|     ...|:|.:.|....
Yeast    63 IAAGGQLTTTTDIENFPGFPESLSGSELMERMRKQSAKFGTNIITE-----TVSKVDLSSKPFRL 122

  Fly   268 -----SNGYVVKYDKIYLATGCSAFRPPIPGVNLENVRTVRELADTKAILASITPESR---VVCL 324
                 .:...|..|.|.||||.||.|..:||   |.....:.:: ..|:.....|..|   :..:
Yeast   123 WTEFNEDAEPVTTDAIILATGASAKRMHLPG---EETYWQQGIS-ACAVCDGAVPIFRNKPLAVI 183

  Fly   325 GSSFIALEAAAGLVSKVQSVTVVGRENVPLKAAFGAEIGQRVLQ-LFEDNKVVMRMESGIAEIVG 388
            |....|.|.|..|......|.::.|     |..|.|.:   ::| ..|.|..::.:.:.:| :..
Yeast   184 GGGDSACEEAEFLTKYASKVYILVR-----KDHFRASV---IMQRRIEKNPNIIVLFNTVA-LEA 239

  Fly   389 NEDGKVSEVVLVDDTR------LPCDLLILGTGSKLNTQFLAKSGVKVNRNGSVD--VTDFLE-- 443
            ..|||:..::.:.:|:      |..:.|....|....|..:         .|.||  .|.:::
Yeast   240 KGDGKLLNMLRIKNTKSNVENDLEVNGLFYAIGHSPATDIV---------KGQVDEEETGYIKTV 295

  Fly   444 -----SNVPDVYVGGDIANA 458
                 ::||..:..||:.::
Yeast   296 PGSSLTSVPGFFAAGDVQDS 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	62/325 (19%)
		Pyr_redox	320..402	CDD:278498	18/85 (21%)
		Reductase_C	505..577	CDD:291425
TRR2	NP_011974.1	TRX_reduct	28..338	CDD:273540	63/333 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345489
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840