DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and LPD1

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_116635.1	Gene:	LPD1 / 850527	SGDID:	S000001876	Length:	499	Species:	Saccharomyces cerevisiae

Alignment Length:	414	Identity:	95/414 - (22%)
Similarity:	167/414 - (40%)	Gaps:	107/414 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 MLRAKRSDLVNNKR-----LKNMVRRKPDDQRVFIVVGGGPSGAVAVETIRQEGFT-------GR 206
            |||.:  .|:||||     ::.:...|..|   .:::||||:|.||.....|.||.       |:
Yeast     1 MLRIR--SLLNNKRAFSSTVRTLTINKSHD---VVIIGGGPAGYVAAIKAAQLGFNTACVEKRGK 60

  Fly   207 LIFVC------------REDYLPYDR--------------VKIS-----KAMNLEIEQLRFRDEE 240
            |...|            ...:|.:..              :||:     ||.:..::||....|.
Yeast    61 LGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIEL 125

  Fly   241 FYKEYDIELWQG------------VAAEKLDTAQKELHCSNGYVVKYDKIYLATGCSAFRPPIPG 293
            .:|:..:..::|            ...:.|:...||.|     ::....|.:|||...  .|.||
Yeast   126 LFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDH-----ILDVKNIIVATGSEV--TPFPG 183

  Fly   294 VNLENVRTVRELADTKAILASITPESRVVCLGSSFIALEAAAGLVSKVQS-VTVVGRENVP-LKA 356
            :.::..:.|   :.|.|:.....|: |:..:|...|.||..: :.|::.| ||||  |..| :.|
Yeast   184 IEIDEEKIV---SSTGALSLKEIPK-RLTIIGGGIIGLEMGS-VYSRLGSKVTVV--EFQPQIGA 241

  Fly   357 AFGAEIGQRVLQLFEDNKVVMRMESGIAEIVGNEDGKVSEVVLVDDTR------LPCDLLILGTG 415
            :...|:.:...:..:...:..::.:.:.....|:|..|.|:| |:||:      |..::|::..|
Yeast   242 SMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIV-VEDTKTNKQENLEAEVLLVAVG 305

  Fly   416 SKLNTQFLA-----KSGVKVNRNGSVDVTDFLESNVPDVYVGGDIA-------NAHIHGLA---- 464
            .:   .::|     |.|::|::.|.:.:.|...|..|.:.|.||:.       .|...|:|
Yeast   306 RR---PYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEM 367

  Fly   465 ----HDRVNIGHYQLAQY-HGRVA 483
                |..||..:.....| |..||
Yeast   368 LKTGHGHVNYNNIPSVMYSHPEVA 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560	95/414 (23%)
		Pyr_redox_2	183..465	CDD:285266	78/359 (22%)
		Pyr_redox	320..402	CDD:278498	21/83 (25%)
		Reductase_C	505..577	CDD:291425
LPD1	NP_116635.1	Pyr_redox_2	24..498	CDD:423044	87/389 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910