DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and MDAR6

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_849839.1	Gene:	MDAR6 / 842697	AraportID:	AT1G63940	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	466	Identity:	110/466 - (23%)
Similarity:	191/466 - (40%)	Gaps:	109/466 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 DDQRVFIVVGGGPSGAVAVETIRQEGFT-GRLIFVCREDYLPYDRVKISKAMNLEIEQLRFR--- 237
            ::.|.|::||||.:...|..|..:.|.. |||..|.:|.|.||:|..::||.....|:...|
plant    58 NENREFVIVGGGNAAGYAARTFVENGMADGRLCIVTKEAYAPYERPALTKAYLFPPEKKPARLPG 122

  Fly   238 ------------DEEFYKEYDIELWQGVAAEKLDTAQKELHCSNGYVVKYDKIYLATGCSAFR-P 289
                        ..::|||..||:.........|..::.|....|..:||..:.:||||:|.| |
plant   123 FHTCVGGGGERQTPDWYKEKGIEVIYEDPVAGADFEKQTLTTDAGKQLKYGSLIIATGCTASRFP 187

  Fly   290 PIPGVNLENVRTVRELADTKAILASITPESRVVCLGSSFIALEAAAGLVSKVQSVTVVGRENVPL 354
            ...|.:|..|..:||:||..:::||:....::|.:|..:|.:|.||..|:.....|:|..|:..|
plant   188 DKIGGHLPGVHYIREVADADSLIASLGKAKKIVIVGGGYIGMEVAAAAVAWNLDTTIVFPEDQLL 252

  Fly   355 KAAFGAEIGQRVLQLFEDNKVVMRMESGIAEIVGNEDGKVSEVVLVDDTRLPCDLLILGTGSK-- 417
            :..|...:.|:..:|:..|.|.....:.|..:....||:||.|.|.|.:.:..|.:::|.|:|
plant   253 QRLFTPSLAQKYEELYRQNGVKFVKGASINNLEAGSDGRVSAVKLADGSTIEADTVVIGIGAKPA 317

  Fly   418 ---LNTQFLAKSGVKVNRNGSVDVTDFLESNVPDVYVGGDIANAHIHGLAHDRV----NIGHYQL 475
               ..|..:.||      .|.:.|.....::.|.::..||:|...:.  .:||:    ::.|.:.
plant   318 IGPFETLAMNKS------IGGIQVDGLFRTSTPGIFAIGDVAAFPLK--IYDRMTRVEHVDHARR 374

  Fly   476 AQYHGRVAAINMCGGVKKL--------EAVPFFFTLIFGKGIRYAG------------------- 513
            :..|        |  ||.|        :.:|:|::.:|    .|.|
plant   375 SAQH--------C--VKSLLTAHTDTYDYLPYFYSRVF----EYEGSPRKVWWQFFGDNVGETVE 425

  Fly   514 --------------HGSYKDVIID-GSMEDFKFVAYFINEADTVTAVASCGRDPIVAQFAELISQ 563
                          .|..|.|::: ||.|:|:.:                   |.:|:...|:.:
plant   426 VGNFDPKIATFWIESGRLKGVLVESGSPEEFQLL-------------------PKLARSQPLVDK 471

  Fly   564 GKCLGRGQIED 574
            .|......:|:
plant   472 AKLASASSVEE 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	83/303 (27%)
		Pyr_redox	320..402	CDD:278498	23/81 (28%)
		Reductase_C	505..577	CDD:291425	15/104 (14%)
MDAR6	NP_849839.1	Pyr_redox_2	83..376	CDD:400379	80/300 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1964
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I2003
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D405030at2759
OrthoFinder	1	1.000	-	-		FOG0001279
OrthoInspector	1	1.000	-	-		mtm1154
orthoMCL	1	0.900	-	-		OOG6_100481
Panther	1	1.100	-	-	O	PTHR43557
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830