DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and ATMDAR2

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_568125.1	Gene:	ATMDAR2 / 831774	AraportID:	AT5G03630	Length:	435	Species:	Arabidopsis thaliana

Alignment Length:	430	Identity:	117/430 - (27%)
Similarity:	182/430 - (42%)	Gaps:	57/430 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 FIVVGGG-PSGAVAVETIRQEGFTGRLIFVCREDYLPYDRVKISKA-MNLEIE------------ 232
            :::|||| .:|..|.|...|....|.|..:.||...||:|..:||. ::||.:
plant     9 YVIVGGGVAAGYAAREFFNQGVKPGELAIISREQVPPYERPALSKGYIHLENKATLPNFYVAAGI 73

  Fly   233 --QLRFRDEEFYKEYDIELWQGVAAEKLDTAQKELHCSNGYVVKYDKIYLATGCSAFRPP---IP 292
              :.:|  .::|||..|||..|....|.|.|.|.|....|.|.||..:..|||.|..|..   :|
plant    74 GGERQF--PQWYKEKGIELILGTEIVKADLAAKTLVSGTGQVFKYQTLLAATGSSVIRLSDFGVP 136

  Fly   293 GVNLENVRTVREL--ADTKAILASITPESRVVCLGSSFIALEAAAGLVSKVQSVTVVGRENVPLK 355
            |.:.:|:..:|||  ||..|.......:.:.|.:|..:|.||..|.|.:....||:|..|...:.
plant   137 GADAKNIFYLRELEDADYLAYAMETKEKGKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMP 201

  Fly   356 AAFGAEIGQRVLQLFEDNKVVMRMESGIAE-IVGNEDGKVSEVVLVDDTRLPCDLLILGTGSKLN 419
            ..|.|.|.. ..:.:..||.:..::..:|. ...|.:|:|:||.|.|...|..|::|:|.|.:..
plant   202 RLFTAGIAS-FYEGYYANKGINIVKGTVASGFTTNSNGEVTEVKLKDGRTLEADIVIVGVGGRPI 265

  Fly   420 TQFLAKSGVKVNRNGSVDVTDFLESNVPDVYVGGDIANAHIHGLAHDRVNIGHYQLAQYHGRVAA 484
            .. |.|..|: ...|.:....|.::::||||..||:|...:. |.::...:.|..    |.|.:|
plant   266 IS-LFKDQVE-EEKGGLKTDGFFKTSLPDVYAIGDVATFPMK-LYNEMRRVEHVD----HARKSA 323

  Fly   485 INMCGGVKKLEA---------VPFFFTLIFGKGIRYAGHGSYKDVII---DGSMEDFKFVAYFIN 537
            ......:|..|.         :|:|::..|....::.|....:.|:.   |......||.:|:|.
plant   324 EQAVKAIKAAEEGNSIPEYDYLPYFYSRAFDLSWQFYGDNVGESVLFGDNDPESPKPKFGSYWIK 388

  Fly   538 EADTV------------TAVASCGR-DPIVAQFAELISQG 564
            |...|            .|:|...| .|.|.....|..:|
plant   389 ERKVVGAFLEGGSPEENNAIAKLARAQPSVESLEVLSKEG 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	92/303 (30%)
		Pyr_redox	320..402	CDD:278498	23/82 (28%)
		Reductase_C	505..577	CDD:291425	17/76 (22%)
ATMDAR2	NP_568125.1	Pyr_redox_2	33..323	CDD:285266	87/299 (29%)
ATMDAR2	NP_568125.1	Pyr_redox	166..248	CDD:278498	23/82 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1964
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I2003
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D405030at2759
OrthoFinder	1	1.000	-	-		FOG0001279
OrthoInspector	1	1.000	-	-		mtm1154
orthoMCL	1	0.900	-	-		OOG6_100481
Panther	1	1.100	-	-	O	PTHR43557
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830