DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and MDAR4

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_189420.1	Gene:	MDAR4 / 822402	AraportID:	AT3G27820	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	398	Identity:	111/398 - (27%)
Similarity:	178/398 - (44%)	Gaps:	54/398 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 VFIVVGGG-PSGAVAVETIRQEGFTGRLIFVCREDYLPYDRVKISKAMNLEIEQLRF-------- 236
            |::::||| .:|..|:|..|:....|.|..:..|...||:|..:||...|.....|.
plant     6 VYVILGGGVAAGYAALEFTRRGVSDGELCIISEEPVAPYERPALSKGFLLPEAPARLPSFHTCVG 70

  Fly   237 -RDE----EFYKEYDIELWQGVAAEKLDTAQKELHCSNGYVVKYDKIYLATGCSAFRPP---IPG 293
             .||    ::||::.|||..|...:.:|..:|.|..|.|..:.|..:.:|||..|.:..   :.|
plant    71 ANDEKLTPKWYKDHGIELVLGTRVKSVDVRRKTLLSSTGETISYKFLIIATGARALKLEEFGVEG 135

  Fly   294 VNLENVRTVRELADTKAILASITPES--RVVCLGSSFIALEAAAGLVSKVQSVTVVGRENVPLKA 356
            .:.|||..:|:|||...:...|...|  ..|.:|..:|.:|.||.||....:||:|..|...:..
plant   136 SDAENVCYLRDLADANRLATVIQSSSNGNAVVIGGGYIGMECAASLVINKINVTMVFPEAHCMAR 200

  Fly   357 AFGAEIGQRVLQLFEDNKVVMRMESGIAEIVG--------NEDGKVSEVVLVDDTRLPCDLLILG 413
            .|..:|.    .|:||    .....|:..|.|        :.:.||:.|.|.|.:.||.||:::|
plant   201 LFTPKIA----SLYED----YYRAKGVKFIKGTVLTSFEFDSNKKVTAVNLKDGSHLPADLVVVG 257

  Fly   414 TGSKLNTQF------LAKSGVKVNRNGSVDVTDFLESNVPDVYVGGDIANAHIHGLAHDRVNIGH 472
            .|.:.||..      :.|.|:|||..        ::|:...||..||:|...:. |..:...:.|
plant   258 IGIRPNTSLFEGQLTIEKGGIKVNSR--------MQSSDSSVYAIGDVATFPVK-LFGEMRRLEH 313

  Fly   473 YQLAQYHGRVAAINMCGGVK--KLEAVPFFFTLIFGKGIRYAGHGSYKDVIIDGSMEDFK-FVAY 534
            ...|:...|.|...:...:|  ..:.:|||::.:|....::.|..: .||:..|..||.| |.||
plant   314 VDSARKSARHAVSAIMDPIKTGDFDYLPFFYSRVFAFSWQFYGDPT-GDVVHFGEYEDGKSFGAY 377

  Fly   535 FINEADTV 542
            ::.:...|
plant   378 WVKKGHLV 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	90/314 (29%)
		Pyr_redox	320..402	CDD:278498	24/89 (27%)
		Reductase_C	505..577	CDD:291425	12/39 (31%)
MDAR4	NP_189420.1	Pyr_redox_2	29..321	CDD:400379	85/308 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1964
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H135034
Inparanoid	1	1.050	117	1.000	Inparanoid score	I2003
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D405030at2759
OrthoFinder	1	1.000	-	-		FOG0001279
OrthoInspector	1	1.000	-	-		mtm1154
orthoMCL	1	0.900	-	-		OOG6_100481
Panther	1	1.100	-	-	LDO	PTHR43557
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830