DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and MDHAR

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_566361.1	Gene:	MDHAR / 820155	AraportID:	AT3G09940	Length:	441	Species:	Arabidopsis thaliana

Alignment Length:	441	Identity:	104/441 - (23%)
Similarity:	183/441 - (41%)	Gaps:	78/441 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 FIVVGGGPSGAVAVETIRQEGF-TGRLIFVCREDYLPYDRVKISKA-MNLEI------------- 231
            ::::|||.:|..|......:|. .|.|..:.:|...|::|.:::|. ::||:
plant     9 YVIIGGGVAGGYAAREFSNQGLKPGELAIISKEPVPPFERPELTKVYIDLEVNPTLANIYVCAGT 73

  Fly   232 -EQLRFRDEEFYKEYDIELWQGVAAEKLDTAQKELHCSNGYVVKYDKIYLATGCSAFRPPIPGV- 294
             |..::  ..:|||..|:|..|....|.|.|.|.|...:|.:.||..:.:|||.:..|....||
plant    74 GEAKQY--PNWYKEKGIDLIVGTEIVKADLASKTLVSDDGKIYKYQTLLIATGSTNIRLSEIGVQ 136

  Fly   295 --NLENVRTVRELADTKAILASI---TPESRVVCLGSSFIALEAAAGLVSKVQSVTVVGRENVPL 354
              :::|:..:||:.|:..:..::   ....:.|.:|..|:.||.::.|.:....||:|..|...:
plant   137 EADVKNIFYLREIEDSDELALAMELYVQRGKAVIIGGGFLGLEISSALRANNHEVTMVFPEPWLV 201

  Fly   355 KAAFGAEIGQRVLQLFEDNKVVMRMESGIAE-IVGNEDGKVSEVVLVDDTRLPCDLLILGTGSKL 418
            ...|.|||.. ..:.:..||.:..::..:|. ...|.||:|:||.|.|...|..::::.|.|::.
plant   202 HRFFTAEIAS-FYESYYANKGIKIIKGTVATGFSTNSDGEVTEVKLEDGRTLEANIVVAGVGARP 265

  Fly   419 NTQFLAKSGVKVNRNGSVDVTDFLESNVPDVYVGGDIANAHIHGLAHDRVNIGHYQLAQYHG--R 481
            .|...  .|......|.:....|.:::|||||..||:|.               :.:..|.|  |
plant   266 ATSLF--KGQLEEEKGGIKTDGFFKTSVPDVYALGDVAT---------------FPMKMYGGTRR 313

  Fly   482 V-----AAINMCGGVKKLEA------------VPFFFTLIFGKGIRYAGHGSYKDVII---DGSM 526
            |     |..:....||.::|            :|:|::..|.....:.|....:.|:.   |...
plant   314 VEHADNARKSAAQAVKAIKAGEEGKTIPDYDYLPYFYSRFFKLSWEFYGENVGESVLFGDNDPKS 378

  Fly   527 EDFKFVAYFINEADTV------------TAVASCGR-DPIVAQFAELISQG 564
            ...||..|::.:...|            .|:|...| .|.|.....|..:|
plant   379 PKPKFGTYWVKDGKVVGVFLEGGTQEEHKAIAKVARAQPSVESLDVLSEEG 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	79/304 (26%)
		Pyr_redox	320..402	CDD:278498	24/82 (29%)
		Reductase_C	505..577	CDD:291425	15/76 (20%)
MDHAR	NP_566361.1	Pyr_redox_2	31..324	CDD:400379	78/312 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1964
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I2003
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D405030at2759
OrthoFinder	1	1.000	-	-		FOG0001279
OrthoInspector	1	1.000	-	-		mtm1154
orthoMCL	1	0.900	-	-		OOG6_100481
Panther	1	1.100	-	-	O	PTHR43557
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830