Protein Alignment CG4199 and PYROXD1

DIOPT Version :9

• Sequence 1: NP_001188537.1
• Gene: CG4199 / 31174
• FlyBaseID: FBgn0025628
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_079130.2
• Gene: PYROXD1 / 79912
• HGNCID: 26162
• Length: 500
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 78/380 - (20%)
• Similarity: 132/380 - (34%)
• Gaps: 123/380 - (32%)

  Fly   174 RKPDDQRVFIVVGGGPSGAVAVETIRQEGFTGRLIFVCREDYLPYDRVKISKAMNLEIEQLRFRD 238
            |.|.....|:|||||.:|....|.:... |..       ||.|......:.||:. ..:|:
Human     5 RPPPTAGKFVVVGGGIAGVTCAEQLATH-FPS-------EDILLVTASPVIKAVT-NFKQI---- 56

  Fly   239 EEFYKEYDIELWQGVAAEK-------LDTAQKEL----HC-----SNGYVVKYDKIYLATGCSAF 287
            .:..:|:|:|........|       :::..|:|    ||     .|.:|  |.|:.|   |:..
Human    57 SKILEEFDVEEQSSTMLGKRFPNIKVIESGVKQLKSEEHCIVTEDGNQHV--YKKLCL---CAGA 116

  Fly   288 RPPIPGVNLENVRTVRELADTKAILASITPESRVVCLGSSFIALEAAAGLVSKVQSVTVVGRENV 352
            :|.:.......|..:|:....:.....:|...|::.:|:..||||    ||.:::...|:..  :
Human   117 KPKLICEGNPYVLGIRDTDSAQEFQKQLTKAKRIMIIGNGGIALE----LVYEIEGCEVIWA--I 175

  Fly   353 PLKA-------AFGAEI---------------GQRVLQLFEDNKVVMRMESGIAEIVGNEDG--- 392
            ..||       |..||.               .:|.....|..|...|.:|. |:.||:..|
Human   176 KDKAIGNTFFDAGAAEFLTSKLIAEKSEAKIAHKRTRYTTEGRKKEARSKSK-ADNVGSALGPDW 239

  Fly   393 ----------------------KVSEVVLVDDTRL------------------------------ 405
                                  :|.::.|.|:.|:
Human   240 HEGLNLKGTKEFSHKIHLETMCEVKKIYLQDEFRILKKKSFTFPRDHKSVTADTEMWPVYVELTN 304

  Fly   406 ----PCDLLILGTGSKLNTQ-FLAKSGVKVNRNGSVDVTDFLESNVPDVYVGGDI 455
                .||.::..||...|.: ||..:...:..:|.:.|.|.:.:::||:|..|||
Human   305 EKIYGCDFIVSATGVTPNVEPFLHGNSFDLGEDGGLKVDDHMHTSLPDIYAAGDI 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	75/371 (20%)
		Pyr_redox	320..402	CDD:278498	25/128 (20%)
		Reductase_C	505..577	CDD:291425
PYROXD1	NP_079130.2	Pyr_redox_2	24..383	CDD:330998	69/361 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..235		7/24 (29%)
		NirB	<300..>494	CDD:330997	16/60 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900