DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and aifm1

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_005165182.1	Gene:	aifm1 / 373125	ZFINID:	ZDB-GENE-030826-11	Length:	748	Species:	Danio rerio

Alignment Length:	411	Identity:	95/411 - (23%)
Similarity:	167/411 - (40%)	Gaps:	108/411 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 FIVVGGGPSGAVAVETIRQEGFTGRLIFVCREDYLPYDRVKISKAM----------NLEIEQ--- 233
            ::::|||.:...|..:||......|::.:..|..|||.|..:||.:          :|..:|
Zfish   271 YLLIGGGTASFAAARSIRARDPGARVLIITEESDLPYMRPPLSKELWFSDDPKVTESLRFKQWNG 335

  Fly   234 ----LRFRDEEFY-KEYDIELWQ--GVA------AEKLDTAQKELHCSNGYVVKYDKIYLATGCS 285
                :.|:...|| ...|:...:  |||      ...:|....::..|:|..:.|:|..:|||
Zfish   336 KERSIYFQPPSFYVSPADLAKVENGGVAVLTDSKVVHMDVRGNKVKLSDGSEISYEKCLIATG-- 398

  Fly   286 AFRPPIPGV--NLENV---------RTV--RELADTKAILASITPESR-VVCLGSSFIALEAAAG 336
                   ||  ||:.:         ||.  |::.|.:: |..|:.|.: :..:|..|:..|.|..
Zfish   399 -------GVPRNLQVIDRAGEEVIKRTTLFRKIEDFRS-LEKISREVKSITIIGGGFLGSELACA 455

  Fly   337 LVSKVQSVTVVGRENVPLKAAFGAEIGQRVLQLFED----NKVV-----------MRME------ 380
            |          ||.:        |:.|..|:|||.:    .||:           :|.|
Zfish   456 L----------GRRS--------ADPGLEVMQLFPEKGNMGKVLPEYLSNWTTEKVRKEGVNVIT 502

  Fly   381 SGIAEIVGNEDGKVSEVVLVDDTRLPCDLLILGTGSKLNTQFLAKSGVKVNRN-GSVDVTDFLES 444
            ..:.:.|..::.|: |:.|.|...:..|.::...|.:.:.:....:|::|:.: |...|...|::
Zfish   503 DAVVKNVTYKNDKL-EIKLKDGRLVKTDHIVAAVGLEPSVELAKSAGLEVDSDFGGYRVNAELQA 566

  Fly   445 NVPDVYVGGDIANAHIHGLAHDRVNIGHYQLAQYHGRVAAINMCGGVKKLEAVPFFFTLIF---- 505
            . .:::|.||.|..:...|...||.  |:..|...||:|..||.|..|     |::...:|
Zfish   567 R-SNIWVAGDAACFYDIKLGRRRVE--HHDHAVVSGRLAGENMTGANK-----PYWHQSMFWSDL 623

  Fly   506 GKGIRYAGHGSYKDVIIDGSM 526
            |..:.|...|     |:|.|:
Zfish   624 GPDVGYEAIG-----IVDSSL 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	76/343 (22%)
		Pyr_redox	320..402	CDD:278498	21/103 (20%)
		Reductase_C	505..577	CDD:291425	7/26 (27%)
aifm1	XP_005165182.1	AIF-MLS	<56..203	CDD:291623
		Pyr_redox_2	274..584	CDD:285266	75/339 (22%)
		Pyr_redox	439..523	CDD:278498	21/102 (21%)
		AIF_C	602..728	CDD:291391	13/48 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810