Protein Alignment CG4199 and aif1

DIOPT Version :10

• Sequence 1: NP_569976.1
• Gene: CG4199 / 31174
• FlyBaseID: FBgn0025628
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001342910.2
• Gene: aif1 / 3361554
• PomBaseID: SPAC26F1.14C
• Length: 575
• Species: Schizosaccharomyces pombe
• Alignment Length: 568
• Identity: 181/568 - (31%)
• Similarity: 290/568 - (51%)
• Gaps: 72/568 - (12%)

  Fly    66 LKENEMKQVDFDEDT-----------------RVLLVKQNDRLLAVGAKCTHYGAPLQTGAL-GL 112
            |.:.:..|::||..:                 .||||:..:...|...||:||||||..|.: ..
pombe    12 LAQKKKFQLEFDPSSVSKNGTKTEAKVVGTEFGVLLVRARNTYFATAGKCSHYGAPLAKGVVTSD 76

  Fly   113 GRVRCPWHGACFNLENGDIEDFPGLDSLPCYRVEVGNEGQVML-------------------RAK 158
            |.:.|||||||||...||:||.|.:.:|..:.|....:|.:.:                   |.|
pombe    77 GHIVCPWHGACFNAATGDVEDTPAIAALRTFPVTEEGDGSLWIEVEDKNDNGASVLQPEGCWRNK 141

  Fly   159 RSDLVNNKRLKNMVRRKPDDQRVFIVVGGGPSGAVAVETIRQEGFTGRLIFVCREDYLPYDRVKI 223
            .:::.|    |..|..:.....| .::|||...:||.|.:|::.|.|::....|||.:||||.|:
pombe   142 ATEVYN----KGSVETEVTAPHV-CIIGGGKGASVAAEYLREKNFKGKITIFTREDEVPYDRPKL 201

  Fly   224 SKAMNLEIEQLRFRDEEFYKEYDIELWQGVAAEKLDTAQKELHCSNGY--VVKYDKIYLATGCSA 286
            ||::..:|.:|..|.:|:|.:.||.........|:|.|:|:::|.:..  ...|.|:.||||...
pombe   202 SKSLLHDISKLALRSKEYYDDLDISFHFNTDVTKIDLAEKKIYCGSDEKPTESYTKLILATGGEP 266

  Fly   287 FRPPIPGVNLENVRTVRELADTKAILASITPES----RVVCLGSSFIALEAAAGLVSKVQSVTVV 347
            .:.||||::.:||..:|.:||... ||::|.|:    .:|.:|||||.||.|  :|.|..:|:|:
pombe   267 NKLPIPGLDSKNVYLLRSIADASK-LAAVTTEAGDKKNIVIIGSSFIGLELA--VVLKDHNVSVI 328

  Fly   348 GRENVPLKAAFGAEIGQRVLQLFEDNKVVMRMESGIAEI--VGNEDGKVSEVVLVDDTRLPCDLL 410
            |.|::|.:...|.|:|..:..|.|.|.:...:|:.|.|:  ..|:..|...:||.|...:|.|::
pombe   329 GMESIPFEKVMGKEVGTALKALHEQNGIAFYLENSIKEVKTSSNDSSKAEHIVLKDGQSIPADVV 393

  Fly   411 ILGTGSKLNTQFLAKSGVKVNRNGSVDVTDFLE-SNVPDVYVGGDIANAHIHGL------AHDRV 468
            ||..|.|.|.::|. :.|.:.::|.|.|.:... ....|||..||||:|...||      :|.|:
pombe   394 ILAAGVKPNLRYLG-NAVSLEKDGGVKVDEHCRVLGAEDVYAVGDIAHAPFAGLPSSGEKSHTRI 457

  Fly   469 NIGHYQLAQYHGRVAAINMCGGVK----KLEAVPFFFTLIFGKGIRYAGHGS---YKDVIIDGSM 526
            .  |:.:|...|||||.::..|.|    .....|:|:: ..||.:||.|:.:   :.||:|.||:
pombe   458 E--HWDVAGNLGRVAADHILFGNKAGYTTKSFTPYFWS-AQGKQLRYCGNNAAEGFDDVVIQGSL 519

  Fly   527 EDFKFVAYFINEADTVTAVASCGRDPIVAQFAELISQGKCLGRGQIED 574
            .|:||..:| .:.:.|..|.|..:||:|:|.|.|..:.....:.|:::
pombe   520 SDYKFACFF-TKGEKVVGVCSIMKDPVVSQCARLFIKDAMPSKSQLKE 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_569976.1	Rieske_AIFL_N	59..154	CDD:239560	36/105 (34%)
		NirB	182..578	CDD:440863	139/415 (33%)
aif1	NP_001342910.2	Rieske_AIFL_N	22..118	CDD:239560	34/95 (36%)
		NirB	158..540	CDD:440863	132/390 (34%)