DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and Trxr-1

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_727251.1	Gene:	Trxr-1 / 31760	FlyBaseID:	FBgn0020653	Length:	596	Species:	Drosophila melanogaster

Alignment Length:	411	Identity:	86/411 - (20%)
Similarity:	140/411 - (34%)	Gaps:	99/411 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 IVVGGGPSG-AVAVETIRQEGFTGRLIFV--------------------CREDYLPYDRVKISKA 226
            ||:|||.:| |.|.|.:........|.||                    |....|.:....:.:|
  Fly   118 IVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEA 182

  Fly   227 MNLEIEQLRFRDEEFYKEYDIELWQGVA--------AEKLDTAQKELHCSNGY------------ 271
            :: |.....:..:|..|....:|.|.|.        ..::|...|::...||.
  Fly   183 VH-EAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAK 246

  Fly   272 ------VVKYDKIYLATGCSAFRPPIPGVNLENVRTVRELADTKAILASITPE-SRVVCLGSSFI 329
                  .:......:|.|.....|.|||        ..|...|...|.|:..| .:.:.:|:.:|
  Fly   247 LKSGERTITAQTFVIAVGGRPRYPDIPG--------AVEYGITSDDLFSLDREPGKTLVVGAGYI 303

  Fly   330 ALEAAAGLVSKVQSVTVVGRENVPLKAAFGAEIGQRVLQLFEDNKVVMRMESGIAEIVGNEDGKV 394
            .||.|..|.......||:.| ::.|: .|..::.:.|....|:..:....::....:...:|||:
  Fly   304 GLECAGFLKGLGYEPTVMVR-SIVLR-GFDQQMAELVAASMEERGIPFLRKTVPLSVEKQDDGKL 366

  Fly   395 ----SEVVLVDDTRLPCDLLILGTGSK-----LNTQFLAKSGVKVNRNGSVDVTDFLESNVPDVY 450
                ..|...::.....|.::...|.|     ||   |..:||.|.:: .:.|.....:||.::|
  Fly   367 LVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLN---LPNAGVTVQKD-KIPVDSQEATNVANIY 427

  Fly   451 VGGDIANAHIHG-------------LAHDRVNIGHYQLAQYHGRVAAI-----NMCGGVKKLEAV 497
            ..|||    |:|             |...|:..|..|...|......:     ..|.|:.:.:||
  Fly   428 AVGDI----IYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAV 488

  Fly   498 PFFFTLIFGKGIRYAGHGSYK 518
            .     .||.......||.||
  Fly   489 K-----QFGADEIEVFHGYYK 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	72/351 (21%)
		Pyr_redox	320..402	CDD:278498	17/85 (20%)
		Reductase_C	505..577	CDD:291425	6/14 (43%)
Trxr-1	NP_727251.1	TGR	113..595	CDD:273624	86/411 (21%)
		NADB_Rossmann	115..>150	CDD:304358	12/31 (39%)
		Pyr_redox	294..368	CDD:278498	16/75 (21%)
		Pyr_redox_dim	468..577	CDD:280934	10/42 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840