DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and C26D10.3

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_495754.3	Gene:	C26D10.3 / 182937	WormBaseID:	WBGene00007744	Length:	475	Species:	Caenorhabditis elegans

Alignment Length:	483	Identity:	101/483 - (20%)
Similarity:	170/483 - (35%)	Gaps:	168/483 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 FIVVGGGPSGAVAVETIRQEGFTGRLIFVCREDYLPYDRVKISKAMNLEIEQLRFRDEEFYKEYD 246
            :|:||||.:|......:.|                      :.::.|||:  :......|.|  .
Worm     3 YIIVGGGIAGVSCASQMLQ----------------------LERSANLEV--IIISASSFVK--S 41

  Fly   247 IELWQ--GVAAEKL--------------------------DTAQKELHCSNGYVVKYDKIYLATG 283
            :|.:|  |...||.                          |:::.|:|..|...:||||:.:|||
Worm    42 VENYQKIGQYGEKFDVKETNCHELFPDSRIRFLNDTVVTWDSSKNEIHLQNNEKLKYDKLCIATG 106

  Fly   284 CSAFRPPIP---GVNLENVRTVRELADTKAIL---ASITPESRVVCLGSSFIALEAAAGLVSKVQ 342
            .   ||...   |::    |.:..|.||::.:   ..:.....::.:|:..||.|    |:.:::
Worm   107 S---RPKFQKELGID----RRIVFLRDTQSAIQLKTKLKNAKNILIVGNGGIATE----LIFELK 160

  Fly   343 SVTVVGRENVP-LKAAFGAE-----IGQRVLQ-LFEDNK---------VVMRMESGIAEIVGNED 391
            :..|......| :.|:|..|     |.:|:|: ..:.||         .|...|| ::|.:.|..
Worm   161 TFDVTWLIKDPWICASFFPEDIEQFIEKRLLKGRIDGNKHDGQQKHLQHVAASES-VSENMNNPS 224

  Fly   392 G--------------KVSE-------------VVLVDDT-----------------RLPCDLLIL 412
            |              |:||             |:...||                 :|..|:.|.
Worm   225 GPALGPDWCSQIDFQKISEKSENRSVTILRNCVITSTDTSQNLSVHYMDKEKMADNQLNPDIFIW 289

  Fly   413 GTGSKLNTQFLAKSG-VKVNRNGSVDVTDFLESNVPDVYVGGDI---ANAHIHGLAHDRVNIGHY 473
            ..|...|::..|.:. :::..|..:.|.|..|:::|:|:..||:   .......|...|
Worm   290 AGGVTANSEVWAMNKMLQITENSGIKVNDACETSLPNVFACGDVCALTTTEPSTLWQQR------ 348

  Fly   474 QL---AQYHGRVAAINMCGGVKKLEAVPFFF------TLIFGKGIRYAG--------HGSYKDVI 521
            ||   |:..|.|....|..||::......:|      |..||..:.:.|        .|.:|.|:
Worm   349 QLWTQARQQGEVCGRAMVAGVEEARMQNMYFELFSHCTTFFGLKVVFLGDYKPERQVEGEWKIVL 413

  Fly   522 IDGSMEDF--------KFV-AYFINEAD 540
            .|...:..        |.| |..|.|.|
Worm   414 RDADNDQLVRCVVVKNKIVGALLIGETD 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	77/379 (20%)
		Pyr_redox	320..402	CDD:278498	25/124 (20%)
		Reductase_C	505..577	CDD:291425	13/53 (25%)
C26D10.3	NP_495754.3	Pyr_redox_2	1..358	CDD:285266	81/398 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810