DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4199 and Gsr

DIOPT Version :9

Sequence 1:	NP_001188537.1	Gene:	CG4199 / 31174	FlyBaseID:	FBgn0025628	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_446358.2	Gene:	Gsr / 116686	RGDID:	621747	Length:	410	Species:	Rattus norvegicus

Alignment Length:	213	Identity:	55/213 - (25%)
Similarity:	86/213 - (40%)	Gaps:	49/213 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 NGYVVKYDKIYLATGCSAFRP---PIPGVNLENVRTVRELADTKAILASITPE---------SRV 321
            ||.......|.:|||.....|   .|||.:|                 .||.:         ||.
  Rat    75 NGKKFTAPHILIATGGVPTVPHENQIPGASL-----------------GITSDGFFQLEDLPSRS 122

  Fly   322 VCLGSSFIALEAAAGLVSKVQSVTVVGRENVPLKAAFGAEI-----------GQRVLQLFEDNKV 375
            |.:|:.:||:| .||::|.:.|.|.:...:..:..:|.:.|           |..||: |...|.
  Rat   123 VIVGAGYIAVE-IAGILSALGSKTSLMIRHDKVLRSFDSLISSNCTEELENAGVEVLK-FSQVKE 185

  Fly   376 VMRMESGI-AEIVGNEDGKVSEVVLVDDTRLPCDLLILGTGSKLNTQ--FLAKSGVKVNRNGSVD 437
            |.:..||: ..:|....|:...|..:.|.    |.|:...|...|::  .|.|.|::.:..|.:.
  Rat   186 VKKTPSGLELHVVTALPGRKPTVTTIPDV----DCLLWAIGRDPNSKGLNLNKLGIQTDDKGHIL 246

  Fly   438 VTDFLESNVPDVYVGGDI 455
            |.:|..:||..||..||:
  Rat   247 VDEFQNTNVKGVYAVGDV 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4199	NP_001188537.1	Rieske_AIFL_N	59..154	CDD:239560
		Pyr_redox_2	183..465	CDD:285266	55/213 (26%)
		Pyr_redox	320..402	CDD:278498	24/93 (26%)
		Reductase_C	505..577	CDD:291425
Gsr	NP_446358.2	gluta_reduc_1	1..410	CDD:273614	55/213 (26%)
		Pyr_redox	121..197	CDD:278498	21/77 (27%)
		Pyr_redox_dim	300..408	CDD:280934
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910