Protein Alignment CG4281 and Gpatch2

DIOPT Version :10

• Sequence 1: NP_569973.1
• Gene: CG4281 / 31171
• FlyBaseID: FBgn0025626
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_001388297.1
• Gene: Gpatch2 / 289362
• RGDID: 1308865
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 751
• Identity: 144/751 - (19%)
• Similarity: 213/751 - (28%)
• Gaps: 327/751 - (43%)

  Fly     1 MDQFSHDLTLALDLTLMDRASGGVGRWGSRRRTRSTGNLPCAPQPTEDSSSSPTDALNQG---HH 62
            |::..|||..||:.: .::|.||....|...|     ||.|   |.:..:........:.   ||
  Rat    26 MEELVHDLVSALEES-SEQARGGFAETGDHSR-----NLSC---PLKRQARKRRGRKRRSYNVHH 81

  Fly    63 HGHHGHHHHHHHTSA----NVDGLDTH-NLKLPASDSDEKAEAMLPLRLPLTLPIRMGALESDSL 122
            ....||.......|:    :.|..:.| |.|...||||:  :.::..|.|           |.:|
  Rat    82 PWETGHCLSEGSDSSLEEPSKDYREKHSNNKKDRSDSDD--QMLVAKRRP-----------SSTL 133

  Fly   123 N-----------ETTFSPARFYKPNSRRKRKIKRMSMEFEFSKDTSHTFTESPLQPSLLSSSGSA 176
            |           |:.|:.........||:||:|||:::......|..|.|:.|
  Rat   134 NNSVRGKRLLWHESDFAVDNLGNRTLRRRRKVKRMAVDLPQDISTKRTMTQPP------------ 186

  Fly   177 TGTIRKRLLKIDATGHRSHLFFCGKRKRSNRDRYHEQDSVKLYALPHSQVDDQHVEQPQHQQQRM 241
                       |.         |       ||:..:.|....|              |:.
  Rat   187 -----------DG---------C-------RDQDMDSDGASQY--------------PEF----- 205

  Fly   242 RPRSYSSTSKPLSDRLLPLNKGLLSKINRMAAQGQQTKHTQKTETKDKDLKCHRSEGP-EGVSLE 305
                                  :.||:                  |.:.||..|.:.| ||..||
  Rat   206 ----------------------IRSKV------------------KKRRLKVIRPKAPEEGAVLE 230

  Fly   306 MEELPDQKDAVQKLPLPSADFTTANFNSISMDTIVPVTDIDALLLSTPPAAPLLRKKAQGQAPGH 370
            .||                               |...|.|.:....|.|:..||.:
  Rat   231 SEE-------------------------------VSQADKDKMEYVEPKASDELRSE-------- 256

  Fly   371 SSSSSSKTERRRRFQTFPQPQLQLQAQSMDCSELYDFLSSSSLSSSTDSEAEVGGHRRHDTDREG 435
                                                  |.||..||||:     |...:|..|:|
  Rat   257 --------------------------------------SDSSSLSSTDA-----GLFTNDEGRQG 278

  Fly   436 DDELTDWPGNEFGPGARYDPKRKLTKKSLLPQIRSDDTIGEDDTLMSGTEAGAVGMEP--PSKSP 498
            |||.:||         .|:.:                         ||...|..|:.|  ..:.|
  Rat   279 DDEQSDW---------FYEKE-------------------------SGGACGIAGVAPWWEEEGP 309

  Fly   499 VQLPESLQD------LSRFQPAGVSEP----IEIQNAC-----SEMETNADGTMPASRQIESEMS 548
            |:|..:|.|      ||...|. :|.|    .:.:.:|     |:....:.|..|:.......:|
  Rat   310 VELDTNLPDPVFESILSGSFPL-MSHPGRRGFQARLSCLHGVPSKNIKKSAGAPPSMMSAPGPIS 373

  Fly   549 GETSNPFLSSSP----------PG----HAQGQEVREIRAGCRRINGERPGFSIKMSVNERIARF 599
            .:....|   ||          ||    |.|.|.:|:.||.    .|.:...|:|.:
  Rat   374 NKRMVHF---SPDAHHHDHWFSPGARTEHGQHQLLRDNRAE----RGHKKSCSVKTA-------- 423

  Fly   600 LQDSQQTQIRLPDIELYETDSMSNLATLYSLTMVVEHGCTVLTKTGNTTQTVSMDHL------QQ 658
               |:||.:.|..:...:.......|.|..      .|.|.....|...|.:...::      ..
  Rat   424 ---SRQTSMHLGSLCTGDIKRRRKAAPLPG------PGPTTTGIVGENAQPILESNIGNRMLQSM 479

  Fly   659 GLQPRADLFGDFKRRCYGEEGEEEGEQQQPLQQDPG 694
            |..|.|.|         |.:|....|..|.:|:..|
  Rat   480 GWTPGAGL---------GRDGRGISEPVQAIQRPKG 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4281	NP_569973.1	None
Gpatch2	NP_001388297.1	G-patch	469..510	CDD:396249	10/47 (21%)