Protein Alignment Sik2 and SKS1

DIOPT Version :9

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_015299.1
• Gene: SKS1 / 856081
• SGDID: S000005947
• Length: 502
• Species: Saccharomyces cerevisiae
• Alignment Length: 467
• Identity: 100/467 - (21%)
• Similarity: 152/467 - (32%)
• Gaps: 194/467 - (41%)

  Fly   141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKS------------------------------ 175
            :.|...||.|.:.:|......:|..|.|:|.:.||
Yeast    10 FRITAQIGSGAYGLVFHVVDILTSREYAVKTVFKSSSMDEFYNKNGLNNNSQVARTTLLQTQLYH 74

  Fly   176 --------------------QLDQTNLQKV--YREVEIMKRLK-HPHIIKLYQVMETKNMIYIVS 217
                                ||.:..|.::  |||:....|:: |.:|:|::||:|:....:||.
Yeast    75 FFKSFQKKLFLPSVDLDSILQLTENELNRLPHYREIAFQLRVQSHGNIVKIHQVLESSIATFIVM 139

  Fly   218 EYASQGEIFDYIAKYGRMSESAARFK--FWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIA 280
            :|..: ::|..|.............|  |.|:.||:::||:.||.|.|:|.||:|||.|.|..:.
Yeast   140 DYYDR-DLFTSIVDDKHFVNHGILIKKVFLQLCSALDHCHRLGIYHCDIKPENVLLDRNDNAYLC 203

  Fly   281 DFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQ-YTGPEI------------------------- 319
            |||.|...|             |.||.|..|.. |..||.
Yeast   204 DFGLSTKSK-------------YLAPNVCVGSSYYMAPERILYCLNTTTNGIHVDECCSSLPTDT 255

  Fly   320 -DIWSLGVVLYVLVCGALPF----------------DGSTLQSLRDRVLSGRFRIPFFMSSECEH 367
             ||||||::|..|.|...|:                |.:.|:.:          :|  :|.|...
Yeast   256 GDIWSLGIILINLTCIRNPWLKAHQKEDNTFQHFANDNNVLKKI----------LP--ISDELFT 308

  Fly   368 LIRRMLVLEPTRRYTIDQIKRHRWMCPELLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIG 432
            ::.::|.|.|..|.                                      |:..:|:|...:.
Yeast   309 VLTKILQLNPYTRI--------------------------------------DMKTLMSEVSSLT 335

  Fly   433 SDKTRAS-------LKKNTY-DHVAAIYLLLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRN 489
            | .||..       |....| .|:.....|....:||                       :|:..
Yeast   336 S-FTREGPLSQVPILSSEVYMTHIIRNENLFLSDLSH-----------------------FSADQ 376

  Fly   490 DHQPTQQQSQQQ 501
            :.|..|||.|||
Yeast   377 EQQQQQQQQQQQ 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	80/348 (23%)
		S_TKc	141..392	CDD:214567	80/348 (23%)
SKS1	NP_015299.1	PKc_like	9..331	CDD:419665	82/384 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930