Protein Alignment Sik2 and KKQ8

DIOPT Version :9

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_012753.2
• Gene: KKQ8 / 853686
• SGDID: S000001651
• Length: 724
• Species: Saccharomyces cerevisiae
• Alignment Length: 436
• Identity: 99/436 - (22%)
• Similarity: 164/436 - (37%)
• Gaps: 107/436 - (24%)

  Fly    33 QHERNEKQLDKPPENLPQNGKTEAKGAEGACSHPPLDALRSS-----------VLLDAGAASPSI 86
            :|.:||..::.....||...|::. ..|......|.|:.|||           |..||...|..:
Yeast   308 KHHKNECDIENALSLLPNVEKSQT-NHEKRTGQSPNDSNRSSPTQGREDYLKIVNPDASLGSDEL 371

  Fly    87 DAIVACKDAL-------LAQKLFASGGGSTPGPSPTSSAVGAGGISGKDLLKLKEPMRVGFYDIE 144
            ..|.:....:       |.:|..           ..:..:|....:.:|  ....|  ||.
Yeast   372 KLINSLSSRIHKSLQNYLQEKNL-----------KPAECIGEQAPTFQD--NYGHP--VGL---- 417

  Fly   145 RTIGKGNFAVVKL-ARHRITKNEVAIKIIDKSQL-----------DQTNLQ----KVYREVEIMK 193
              :|.|.:..||| ||.|..|:....:....|:.           ..::|:    |:..|..|..
Yeast   418 --VGAGAYGEVKLCARLRNEKDSPPFETYHDSKYIYYAVKELKPKPDSDLEKFCTKITSEFIIGH 480

  Fly   194 RLKH---------PHIIKLYQVMETKNMIYIVSEYASQGEIFDYIA----KYGRMSESAARFKFW 245
            .|.|         |:|:.::.::|..:....|.|:...|:::..:.    ..||:....|.....
Yeast   481 SLSHYHKNGKKPAPNILNVFDILEDSSSFIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMK 545

  Fly   246 QIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATW----------CGS 300
            |::..|::.|..||.|.|||.||:|...:..:||.|||.|:.|:     ..|          .||
Yeast   546 QLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVFQ-----TAWERRVHAQKGIIGS 605

  Fly   301 PPYAAPEVFEGKQYTGPE-IDIWSLGVVLYVLVCG-------ALPFDGSTLQSLRDRVLSGRFRI 357
            .||.|||.|...:|..|. ||.||.|||...::.|       :...|.|..:..::.....:||:
Yeast   606 EPYVAPEEFVDGEYYDPRLIDCWSCGVVYITMILGHYLWKVASREKDMSYDEFYKEMQRKNQFRV 670

  Fly   358 PFFMSSECEHL-----------IRRMLVLEPTRRYTIDQIKRHRWM 392
                ..|.:|:           :.|:...||.:|.::.::...:||
Yeast   671 ----FEELKHVNSELATNRKIALYRIFQWEPRKRISVGKLLDMQWM 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	73/309 (24%)
		S_TKc	141..392	CDD:214567	73/308 (24%)
KKQ8	NP_012753.2	PKc_like	418..712	CDD:419665	73/302 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840