Protein Alignment Sik2 and PRR2

DIOPT Version :9

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_010067.1
• Gene: PRR2 / 851312
• SGDID: S000002373
• Length: 699
• Species: Saccharomyces cerevisiae
• Alignment Length: 417
• Identity: 98/417 - (23%)
• Similarity: 174/417 - (41%)
• Gaps: 117/417 - (28%)

  Fly   115 TSSAVGAGGIS-----------------------GKDLLKLKEPMRVGFYDIERTIGKGNFAVVK 156
            |||.|..|..|                       ..||:..|      :.|::..:|:|:...||
Yeast   318 TSSPVSTGSFSLMIENEDSDRDQIIQALYSNIEASTDLVSRK------YRDLDVVLGEGSGGKVK 376

  Fly   157 LARHRITKNEV-AIKII---DKSQLDQTNLQKVYREVEIMKRLKHPHIIKLYQVMETKNMIYIVS 217
            |.: |:..|:| |:|..   .|.:.::..::.:..|..|...||:|:|.:..:::..|..|:.:.
Yeast   377 LVQ-RVLDNKVFALKEYRSKKKRESERKYIKNIISEYCIASTLKNPNICETLEILYEKGKIFQIL 440

  Fly   218 EYASQGEIFDYIAKYGRMSES------AARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMN 276
            ||. :.::|..:     |||.      ...||  |:|:.|:|.|..|:.|||||.:|.::.....
Yeast   441 EYC-EYDLFSLV-----MSEKMHYEEICCLFK--QLINGVKYLHDIGLSHRDLKLDNCVVTRRGI 497

  Fly   277 IKIADFGFSNHFK---PGELLAT--WCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCGAL 336
            :|:.|||.|:.|.   ..:::..  ..||.||.:||||...:|....:|:||:|::.:.::....
Yeast   498 LKLIDFGASSVFHYPLSSQMIEANGIVGSDPYLSPEVFYFNEYDPRALDVWSVGIIFFCMITRRF 562

  Fly   337 PF--------------DGSTLQSLRDRV----------------------LSGRF---RIPFFMS 362
            |:              .|..:.|.:|.|                      :...|   |:|
Yeast   563 PWKYPKVKDVQFKAFCSGRGVSSFKDLVTRPATDDSNNYDNDGYEEGVIDMGPNFILHRLP---- 623

  Fly   363 SECEHLIRRMLVLEPTRRYTIDQIKRHRWMCPELLEHVLIAKYNLGAERQTSVEPSEDILRIM-- 425
            .|...::||:|.:.|.||.||:.|.:..|:  :.:|...:    :||     ..|:|..|||:
Yeast   624 EETHKIMRRILEVSPFRRITINGILQDGWI--KEIETCQV----VGA-----ASPNEASLRIINK 677

  Fly   426 AEYVGIGSDKTRASLKKNTYDHVAAIY 452
            ..::....|:        .|.|:..::
Yeast   678 GNHIHTNIDQ--------RYAHIGGLH 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	77/305 (25%)
		S_TKc	141..392	CDD:214567	77/304 (25%)
PRR2	NP_010067.1	PKc_like	367..653	CDD:419665	76/298 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345292
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840