DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sik2 and PSK1

DIOPT Version :10

Sequence 1:NP_569972.1 Gene:Sik2 / 31170 FlyBaseID:FBgn0025625 Length:1398 Species:Drosophila melanogaster
Sequence 2:NP_009385.2 Gene:PSK1 / 851216 SGDID:S000000015 Length:1356 Species:Saccharomyces cerevisiae


Alignment Length:418 Identity:115/418 - (27%)
Similarity:185/418 - (44%) Gaps:64/418 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 SEESQPPEDQKKKQPQ-----------------HERNEKQLDKP-----PENL-----PQNGKTE 55
            ||:.|.|.:..|...:                 :.|::.|..|.     .|||     ..:..||
Yeast   958 SEQEQVPLENDKDSGEMMLADPEMKHKLELARIYSRDKSQFVKEGNFKVDENLIISKISLSPSTE 1022

  Fly    56 AKGAEGACSHPPLDALRSSVLLDAGAASPSIDAIVACKDALLAQKLFASGGGSTPGPSPTSSAVG 120
            :. |:...|...|..|....|:|..|....:......:|.::......:...||...:|..: :|
Yeast  1023 SL-ADSKSSGKGLSPLEEEKLIDENATENGLAGSPKDEDGIIMTNKRGNQPVSTFLRTPEKN-IG 1085

  Fly   121 AGGISGKDLLKLKEPMRVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQL------DQ 179
            |    .|.:.|..:     |..::: :|:|.:..|.|..|:..:..|.||:|.|.::      ..
Yeast  1086 A----QKHVKKFSD-----FVSLQK-MGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRD 1140

  Fly   180 TNLQKVYREVEIMKRL-KHPH--IIKLYQVMETKNMIYIVSEYASQGE-----IFDYIAKYGRMS 236
            ..|..:..|::||..| |.||  |::|....|..:..||  |....||     :||.|.....|:
Yeast  1141 RKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYI--ETPVHGETGCIDLFDLIEFKTNMT 1203

  Fly   237 ESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSP 301
            |..|:..|.|:::.:::.|.:||||||:|.||:::|....:||.|||.:.:.|.|. ...:.|:.
Yeast  1204 EFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGP-FDVFVGTI 1267

  Fly   302 PYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSG--RFRIPFFMSSE 364
            .||||||..|..|.|...|||::|::||.:|....||...      |.:|.|  :|.....:|.:
Yeast  1268 DYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNI------DEILEGDLKFNNAEEVSED 1326

  Fly   365 CEHLIRRMLVLEPTRRYTIDQIKRHRWM 392
            |..||:.:|.....:|.|||.|...:|:
Yeast  1327 CIELIKSILNRCVPKRPTIDDINNDKWL 1354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sik2NP_569972.1 STKc_SIK 140..392 CDD:270973 86/267 (32%)
UBA_SIK 418..458 CDD:270523
PSK1NP_009385.2 STKc_PASK 1095..1354 CDD:270906 86/273 (32%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.