Protein Alignment Sik2 and CIPK21

DIOPT Version :10

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_568860.1
• Gene: CIPK21 / 835868
• AraportID: AT5G57630
• Length: 416
• Species: Arabidopsis thaliana
• Alignment Length: 364
• Identity: 131/364 - (35%)
• Similarity: 193/364 - (53%)
• Gaps: 51/364 - (14%)

  Fly   137 RVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQ-KVYREVEIMKRLKHPHI 200
            ::|.|:|.||||:||||.|||.........||:|||||:.:.|..|: :|.||:..||.|.||:|
plant     8 KIGKYEIGRTIGEGNFAKVKLGYDTTNGTYVAVKIIDKALVIQKGLESQVKREIRTMKLLNHPNI 72

  Fly   201 IKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLK 265
            :::::|:.||..|.||.||.|.|::.|.:.:. :|.||.||..|.|:|.||:|||.:|:.|||||
plant    73 VQIHEVIGTKTKICIVMEYVSGGQLSDRLGRQ-KMKESDARKLFQQLIDAVDYCHNRGVYHRDLK 136

  Fly   266 AENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYV 330
            .:|||||...|:|::|||.|...|.|::|:|.||||.|.|||:...|.|:|..:|:||.||:|:.
plant   137 PQNLLLDSKGNLKVSDFGLSAVPKSGDMLSTACGSPCYIAPELIMNKGYSGAAVDVWSCGVILFE 201

  Fly   331 LVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQ-IKRHRWMCP 394
            |:.|..|||..||..|..::|...:..|...:.|.:.||..:|...|..|.|:.: |.:..|
plant   202 LLAGYPPFDDHTLPVLYKKILRADYTFPPGFTGEQKRLIFNILDPNPLSRITLAEIIIKDSW--- 263

  Fly   395 ELLEHVLIAKYNLG---AERQTSVEPSEDILRIMA-----------EYVGIGSD----------- 434
                      :.:|   ...|.|....:::..|.|           :.:.:.||
plant   264 ----------FKIGYTPVYHQLSDSIKDNVAEINAATASSNFINAFQIIAMSSDLDLSGLFEEND 318

  Fly   435 ----KTRASLKKNTYDHV-----AAIYLLLQ-DRVSHKK 463
                |||...|....:.:     ||.|:.|. :|:.|.|
plant   319 DKRYKTRIGSKNTAQETIKKIEAAATYVSLSVERIKHFK 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	111/253 (44%)
		UBA_SIK	418..458	CDD:270523	12/71 (17%)
CIPK21	NP_568860.1	Protein Kinases, catalytic domain	11..263	CDD:473864	111/252 (44%)
		CIPK_C	297..411	CDD:213380	13/61 (21%)