Protein Alignment Sik2 and AT5G21222

DIOPT Version :10

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_850859.2
• Gene: AT5G21222 / 832244
• AraportID: AT5G21222
• Length: 831
• Species: Arabidopsis thaliana
• Alignment Length: 951
• Identity: 229/951 - (24%)
• Similarity: 364/951 - (38%)
• Gaps: 257/951 - (27%)

  Fly   138 VGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQ-LDQTNLQKVYREVEIMKRLKHPHII 201
            ||.|::.|.||:.||..::.|....|.:.||:.|:||.: |.....:::.||:.|||.:.||:::
plant    10 VGKYEVGRLIGECNFGKLRSAVDTETGDPVALMILDKDKVLKHKMAEQIKREISIMKLINHPNVV 74

  Fly   202 KLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKA 266
            :||:|:.:|..||||.|:.|.|::||.|...|||:|..|:..|.|:|:||:|||.:|:.|||||.
plant    75 QLYEVLASKAKIYIVLEFISGGKLFDKIKNDGRMNEDEAQRYFQQLINAVDYCHSRGVYHRDLKP 139

  Fly   267 ENLLLDLNMNIKIADFG---FSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVL 328
            ||||||...|:|:|:||   .|.......|..|.||:|.||||||...:.|.|.:.|:||.||:|
plant   140 ENLLLDAQENLKVAEFGLIALSQQAGGDGLRHTACGNPDYAAPEVLNDQGYDGAKADLWSCGVIL 204

  Fly   329 YVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWMC 393
            :||:.|.|||:.|:|.:|..::.|..|..|.::||..::||.|:|...|..|.||
plant   205 FVLLAGYLPFEDSSLTTLYKKISSADFSCPPWLSSGVKNLIVRILDPNPMTRITI---------- 259

  Fly   394 PELLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIGSDKTRASLKKNTYDHVAAIYLLLQDR 458
            ||:||.|...|                                         |:..|::
plant   260 PEILEDVWFKK-----------------------------------------DYKPAVF------ 277

  Fly   459 VSHKKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQSQQQSKTISTSSILAKDQCHKRLSRH 523
              .:|:::|.....|:...:...|:             |.:.....|.:......|      .|.
plant   278 --EEKKEANLADVEAVFKDSEEGRV-------------QLRSFPCVICSGGTTCGD------VRS 321

  Fly   524 QTVLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVEVDASGIPLPMR 588
            :|.||:                       |.::...|...||.....:..|..       |..:.
plant   322 RTKLMN-----------------------GLIERGRPQEAHSIFNTLIEEGHK-------PSLIT 356

  Fly   589 YTPLPTAASPAP--SNCSSTSSRVGRHSLSSSSPRSHRPVAISLSIDNNPSLANLR-----CREM 646
            ||.|.||.:...  .:..|..|:|.::.|...:      :..:..|:.:....||.     ..:|
plant   357 YTTLVTALTRQKHFHSLLSLISKVEKNGLKPDT------ILFNAIINASSESGNLDQAMKIFEKM 415

  Fly   647 MEAGGGPV-----------GAVG-VPLASKQLHQTISEFIIKQSTEDCRALLQ---QSTAVAEGK 696
            .|:|..|.           |.:| :..:|:.|...:.:.:::.:...|..|:|   ....:.|..
plant   416 KESGCKPTASTFNTLIKGYGKIGKLEESSRLLDMMLRDEMLQPNDRTCNILVQAWCNQRKIEEAW 480

  Fly   697 DDPPKAESSVGGVPPPASTTPTSSTAGPESGSAPCPGE-------------INGKTIKTMSSSSS 748
            :...|.:|.  ||.|...|..|.:.|....||. |..|             .|.:|..|:.:...
plant   481 NIVYKMQSY--GVKPDVVTFNTLAKAYARIGST-CTAEDMIIPRMLHNKVKPNVRTCGTIVNGYC 542

  Fly   749 FDSKANLGQSFRYKMSAEASK----LFQTLQESPLPVEQRTKRRVHVGSTNGSGGDSGQETNDAK 809
            .:.|......|.|:|......    :|.:|          .|..:::...:|.|     |..|..
plant   543 EEGKMEEALRFFYRMKELGVHPNLFVFNSL----------IKGFLNINDMDGVG-----EVVDLM 592

  Fly   810 S----NGDSRSEKKVLAQGSSSTD-EGCE---TDQGNDPGSASQESKGSNGGGSGNANGG--PTS 864
            .    ..|..:...::...||..| :.||   ||.                     ..||  |..
plant   593 EEFGVKPDVVTFSTLMNAWSSVGDMKRCEEIYTDM---------------------LEGGIDPDI 636

  Fly   865 HSSSDLTRLVGTTTSGQSHKMRSYASSSSSSGV----------LAG--SAGSYSKS--------- 908
            |:.|.|.:  |...:|:..|.....:.....||          ::|  |||...|:
plant   637 HAFSILAK--GYARAGEPEKAEQILNQMRKFGVRPNVVIYTQIISGWCSAGEMKKAMQVYKKMCG 699

  Fly   909 ---LSQNLSRGSSKSNCSGPYDSLDFALPSGK-----GSLPSCMGSSSMLATPTPASASPAG--- 962
               ||.||:          .|::|.:.....|     ..|...|...:::.|.........|
plant   700 IVGLSPNLT----------TYETLIWGFGEAKQPWKAEELLKDMEGKNVVPTRKTMQLIADGWKS 754

  Fly   963 ISSEHSSERSLYGSHNSCIHMPGALPLGLGLPQSSASTPTP 1003
            |...:|::.:..||..|....       |.:|.:.||:.:|
plant   755 IGVSNSNDANTLGSSFSTSSK-------LNIPNNIASSRSP 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	107/255 (42%)
		UBA_SIK	418..458	CDD:270523	2/39 (5%)
AT5G21222	NP_850859.2	Protein Kinases, catalytic domain	12..267	CDD:473864	111/264 (42%)
		PPR_2	318..364	CDD:463778	15/81 (19%)
		PPR repeat	321..348	CDD:276811	7/49 (14%)
		PLN03218	<342..>740	CDD:215636	85/461 (18%)
		PPR repeat	356..383	CDD:276811	8/26 (31%)
		PPR repeat	389..418	CDD:276811	4/34 (12%)
		PPR repeat	424..453	CDD:276811	4/28 (14%)
		PPR repeat	460..489	CDD:276811	5/28 (18%)
		PPR repeat	502..525	CDD:276811	5/23 (22%)
		PPR_2	529..576	CDD:463778	10/56 (18%)
		PPR repeat	533..560	CDD:276811	6/26 (23%)
		PPR repeat	566..595	CDD:276811	7/43 (16%)
		PPR repeat	601..629	CDD:276811	7/48 (15%)
		PPR repeat	636..665	CDD:276811	6/30 (20%)
		PPR repeat	671..697	CDD:276811	5/25 (20%)
		PPR repeat	707..736	CDD:276811	6/38 (16%)