Protein Alignment Sik2 and CIPK2

DIOPT Version :10

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_196324.1
• Gene: CIPK2 / 830598
• AraportID: AT5G07070
• Length: 456
• Species: Arabidopsis thaliana
• Alignment Length: 396
• Identity: 140/396 - (35%)
• Similarity: 207/396 - (52%)
• Gaps: 49/396 - (12%)

  Fly   141 YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNL-QKVYREVEIMKRLKHPHIIKLY 204
            |::.|.:|:|.||.|...|...|...||||:|||.::.:..| |::.||:.:|:..|||::::||
plant    12 YEVGRLLGQGTFAKVYFGRSNHTNESVAIKMIDKDKVMRVGLSQQIKREISVMRIAKHPNVVELY 76

  Fly   205 QVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAENL 269
            :||.||:.||.|.||...||:|:.:|| |::.|..|...|:|:||||::||.:|:.|||:|.|||
plant    77 EVMATKSRIYFVIEYCKGGELFNKVAK-GKLKEDVAWKYFYQLISAVDFCHSRGVYHRDIKPENL 140

  Fly   270 LLDLNMNIKIADFGFS---NHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVL 331
            |||.|.|:|::|||.|   :..:...||.|.||:|.|.||||...|.|.|.:.||||.||||:||
plant   141 LLDDNDNLKVSDFGLSALADCKRQDGLLHTTCGTPAYVAPEVINRKGYEGTKADIWSCGVVLFVL 205

  Fly   332 VCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWMCPEL 396
            :.|.|||..:.|..:..::....|:.|.:.:.|.:.|:.:||......|.||.:||...|....|
plant   206 LAGYLPFHDTNLMEMYRKIGKADFKCPSWFAPEVKRLLCKMLDPNHETRITIAKIKESSWFRKGL 270

  Fly   397 LEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIGSDKT--------RASLKKNTYDHVAAIYL 453
              |:...|.. ..|:|...|.:..:     |..|.|.::.        .|:|  |.:|.:|.
plant   271 --HLKQKKME-KMEKQQVREATNPM-----EAGGSGQNENGENHEPPRLATL--NAFDIIAL--- 322

  Fly   454 LLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQSQQQSKTISTSSILAKDQCHK 518
                        |.|.|.:.|...      :|..|.....:|:.:   |:.||....:||  |.|
plant   323 ------------STGFGLAGLFGD------VYDKRESRFASQKPA---SEIISKLVEVAK--CLK 364

  Fly   519 RLSRHQ 524
            ...|.|
plant   365 LKIRKQ 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	109/254 (43%)
		UBA_SIK	418..458	CDD:270523	8/47 (17%)
CIPK2	NP_196324.1	Protein Kinases, catalytic domain	11..265	CDD:473864	109/253 (43%)
		CIPK_C	315..428	CDD:213380	19/82 (23%)