Protein Alignment Sik2 and Smok3c

DIOPT Version :9

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_001297632.1
• Gene: Smok3c / 622486
• MGIID: 3647925
• Length: 504
• Species: Mus musculus
• Alignment Length: 463
• Identity: 139/463 - (30%)
• Similarity: 229/463 - (49%)
• Gaps: 72/463 - (15%)

  Fly   119 VGAGGISGKDLLKLKEPM--RVGF---YDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLD 178
            :|.|.....:.|:.|.|.  ..||   |.:..|||.|..|.||||:||:|...||:|.|
Mouse     1 MGPGSQQKSEKLRCKPPFSNMDGFHAQYVMLETIGHGGCATVKLAQHRLTGTHVAVKTI------ 59

  Fly   179 QTNLQK-------VYREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMS 236
                ||       :..||:::....||::|.|.||:|||..:|::.|......::.:|.|.|.:.
Mouse    60 ----QKRGYWCILIMSEVDLLMMADHPNVISLLQVIETKKKVYLIMELCEGKSLYQHIRKAGYLQ 120

  Fly   237 ESAARFKFWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSP 301
            |..||..|.|::||:.|||.:||||||||.:|::::.:..:||.|||.|...|||:.|..:||:.
Mouse   121 EHEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLSTKVKPGQKLNLFCGTY 185

  Fly   302 PYAAPEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECE 366
            |::||||.....|.||:||:|:||||||.:|.|.:|||..:::.|..|:|:|::.||..:|:|..
Mouse   186 PFSAPEVLLSTPYDGPKIDVWTLGVVLYFMVTGKIPFDACSIKRLVKRILAGKYSIPSRLSAELR 250

  Fly   367 HLIRRMLVLEPTRRYTIDQIKRHRWMC------PELLEHVLIAKYNLGAERQTSVEPSEDILRIM 425
            .|:..::...|..|.|:.::..|.|:.      |:            ..|.||.::|...|::.|
Mouse   251 DLLSLLMTANPKLRPTVAEVMVHPWVTEGSGVFPD------------PCEEQTPLKPDPAIVKAM 303

  Fly   426 AEYVGIGSDKTRASLKKNTYDHVAAIYLLLQDRVSHKKEQSNGLGASALASST--------SASR 482
            . ::|..:.....||::..::...|.|.||:.::  .||......|..:..|.        :|:.
Mouse   304 G-HIGFQAQDIEDSLRQRKFNQTMASYCLLKKQI--LKECDRPTRARPVNPSVTPFPSLVDTATT 365

  Fly   483 MIYSSRNDHQPT--------------QQQSQQQSKTISTSSILAKDQCHKRLSRHQTVLMSERNA 533
            .:...|.:::||              :..|:::.:.:|..|:|.:       .||....|.....
Mouse   366 CLGLRRRENEPTCPWSSANRQVSVCGKSTSKKRDRRVSWPSVLGR-------PRHTAPTMDHTRT 423

  Fly   534 HAGATPTV 541
            ...:.|.:
Mouse   424 RTRSVPCI 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	102/261 (39%)
		S_TKc	141..392	CDD:214567	101/257 (39%)
Smok3c	NP_001297632.1	STKc_AMPK-like	27..275	CDD:270905	101/257 (39%)
		UBA_MARK_Par1	295..334	CDD:270522	10/39 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810