Protein Alignment Sik2 and grp

DIOPT Version :9

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 440
• Identity: 123/440 - (27%)
• Similarity: 195/440 - (44%)
• Gaps: 75/440 - (17%)

  Fly   115 TSSAVGAGGISGKDLLKLKEPMRVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIID-KSQLD 178
            |.:..|.|..:.::.        |..:.:.:|:|:|.:..|||..:|.|...||:|::| |...|
  Fly     4 TLTEAGTGPAATREF--------VEGWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPD 60

  Fly   179 QTNLQKVYREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFK 243
            ..|  .|.:||.|.|.|:..||::.:......::.||..|||:.||:||.|.....|.:..|:..
  Fly    61 AAN--SVRKEVCIQKMLQDKHILRFFGKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRY 123

  Fly   244 FWQIISAVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFK---PGELLATWCGSPPYAA 305
            |.|::|.:.|.|::||.|||||.||||||.:.|:||:|||.:..|:   ...||...||:.||.|
  Fly   124 FTQLLSGLNYLHQRGIAHRDLKPENLLLDEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVA 188

  Fly   306 PEVFEGKQYTGPEIDIWSLGVVLYVLVCGALPFDG-----STLQSLRDRVLSGRFRIPFF-MSSE 364
            |||.: |.|.....|:||.||:|..::.|.||:|.     :...:.||.. ..:.:.|:. :.:.
  Fly   189 PEVLQ-KAYHAQPADLWSCGVILVTMLAGELPWDQPSTNCTEFTNWRDND-HWQLQTPWSKLDTL 251

  Fly   365 CEHLIRRMLVLEPTRRYTIDQIKRHRWMCPELLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYV 429
            ...|:|::|...|..|.|:::...|:|...:..::          ||...:..|...|.|.
  Fly   252 AISLLRKLLATSPGTRLTLEKTLDHKWCNMQFADN----------ERSYDLVDSAAALEIC---- 302

  Fly   430 GIGSDKTRASLKKNTYDHVAAIYLLLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRN-DHQP 493
               |.|.:                  :.|:......||||..|.             ||| ..||
  Fly   303 ---SPKAK------------------RQRLQSSAHLSNGLDDSI-------------SRNYCSQP 333

  Fly   494 TQQQSQQQSKTISTSSILAKDQCHKRLSRHQTVLMSERNAHAGATPTVPD 543
            ...........:...|..:|:....|    ||:....|.:::.:.|.:.|
  Fly   334 MPTMRSDDDFNVRLGSGRSKEDGGDR----QTLAQEARLSYSFSQPALLD 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	92/261 (35%)
		S_TKc	141..392	CDD:214567	92/260 (35%)
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	92/262 (35%)
		S_TKc	22..278	CDD:214567	92/259 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010