Protein Alignment Sik2 and CG4629

DIOPT Version :10

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 145/478 - (30%)
• Similarity: 243/478 - (50%)
• Gaps: 54/478 - (11%)

  Fly   137 RVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKII--DKSQLDQTNLQKVYREVEIMKRLKHPH 199
            |:|.|.....||:|||:.||||.|::|:::||||::  |::.||...|:.:..|:..::.:.||:
  Fly    62 RIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPN 126

  Fly   200 IIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDL 264
            |::|::|:||...:|:|:|:...||::::|.:.|.:.|..|.....|::.||::.|..|.||||:
  Fly   127 ILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDI 191

  Fly   265 KAENLLLDLNMNIKIADFGFSNHFKPG--ELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVV 327
            ||||:||.....:|:||||||.....|  :.|.|:||||||||||:|....|.|..:|:|:||::
  Fly   192 KAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGIL 256

  Fly   328 LYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWM 392
            ||.:|.|.:||...|:..|:..:|.|.:.:|..:|..|..||:|:|:..|.:|.|||.:...:::
  Fly   257 LYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFV 321

  Fly   393 -CPELLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIGSDKTRASLKKNTYDHVAAIYLLLQ 456
             ||:|...::..:.|         :.::.:.|.:. :|...|.:.|.|..             |:
  Fly   322 TCPKLSADLMQWEIN---------QHTKPVKRSIF-WVRSKSHRLRKSAS-------------LR 363

  Fly   457 DRVSH--KKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQSQQQSKTISTSSILAKDQCHKR 519
            ||.:.  ||        .|::.:|.....:: .:|..||.:...:   ..:..||.|.:.|..::
  Fly   364 DRYAEVVKK--------PAISMNTRQQDEMF-VQNFLQPIEMGHE---LLVPVSSQLKEPQSTEQ 416

  Fly   520 LSRHQTVLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVEVDASGIP 584
            ..|.....|...:.....||...:|           :..|...|.|..:..:|...||| |...|
  Fly   417 AKRPTRRYMFCGSLKKKVTPMETEP-----------EKQLANGGQSIGSAKINPWNVEV-AEDCP 469

  Fly   585 LPMRYTPLPTAASPAPSNCSSTS 607
            |...|.....:....|:|....|
  Fly   470 LFKNYDAETGSCVMLPTNTEDLS 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	101/255 (40%)
		UBA_SIK	418..458	CDD:270523	6/39 (15%)
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	102/257 (40%)