Protein Alignment Sik2 and Nim1k

DIOPT Version :10

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: XP_006232044.1
• Gene: Nim1k / 310376
• RGDID: 1308116
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 331
• Identity: 133/331 - (40%)
• Similarity: 206/331 - (62%)
• Gaps: 6/331 - (1%)

  Fly   137 RVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYREVEIMKRLKHPHII 201
            |:|||.|...||.|||:.|||..|.:||.:|||||:||::|||...:.:.||:..|::|.||:|:
  Rat    70 RIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIV 134

  Fly   202 KLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKA 266
            :||:|:||.:.:::|.|||..||:|..|:..|::||..::..|.||:|||::.|:..|:||||||
  Rat   135 RLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKA 199

  Fly   267 ENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVL 331
            ||:....:..:|:.|||||...|.||:|.|:||||||||||:|..:.|.|..:|||:|||:||.:
  Rat   200 ENVFYTSSTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFM 264

  Fly   332 VCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWM---- 392
            |.|.:||...|:..|:..:|.|.:.||..:|..|..|||.:|...|..||.|:.|..:.||
  Rat   265 VTGTMPFRAETVAKLKKSILEGAYSIPQHVSEPCHRLIRGVLQPTPAERYGINYIMSNEWMRGVP 329

  Fly   393 CPELLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIGSDKTRASLKKNTYDHVAAIYLLLQD 457
            .|..||...:...:|  ...::::..|:.::...|::||..:..|.:..::....:..:|.::..
  Rat   330 YPSPLEPFQLDPKHL--SETSTLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILH 392

  Fly   458 RVSHKK 463
            ||..:|
  Rat   393 RVQRRK 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	116/251 (46%)
		UBA_SIK	418..458	CDD:270523	6/39 (15%)
Nim1k	XP_006232044.1	STKc_NIM1	71..325	CDD:270977	117/253 (46%)