| Sequence 1: | NP_569972.1 | Gene: | Sik2 / 31170 | FlyBaseID: | FBgn0025625 | Length: | 1398 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_056006.1 | Gene: | SIK2 / 23235 | HGNCID: | 21680 | Length: | 926 | Species: | Homo sapiens |
| Alignment Length: | 1325 | Identity: | 404/1325 - (30%) |
|---|---|---|---|
| Similarity: | 529/1325 - (39%) | Gaps: | 484/1325 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 135 PMRVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYREVEIMKRLKHPH 199
Fly 200 IIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDL 264
Fly 265 KAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLY 329
Fly 330 VLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWMCP 394
Fly 395 EL-LEHVLIAKYNLGAERQTSV-EPSEDILRIMAEYVGIGSDKTRASLKKNTYDHVAAIYLLLQD 457
Fly 458 RV-SHKKEQSNGLGASALASSTSASRMIYSSRNDHQPTQQQ---SQQQSKTISTSSILAKDQCHK 518
Fly 519 RLSRHQTVLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVEVDASGI 583
Fly 584 PLPMRYTPLPTAASPAPSNCSSTSSRVGRHSLSSSSPRSHRPVAISLSIDNNPSLANLRCREMME 648
Fly 649 AGGGPVGAVGVPLASKQLHQTISEFIIKQSTEDCRALLQQSTAVAEGKDDPPKAESSVGGVPPPA 713
Fly 714 STTPTSSTAGPESGSAPCPGEINGKTIKTMSSSSSFDSKANLGQSFRYKMSAEASKLFQTLQESP 778
Fly 779 LPVEQRTKRRVHVGSTNGSGGDSGQETNDAKSNGDSRSEKKVLAQGSSSTDEGCET--DQGNDPG 841
Fly 842 SASQESKGSNGGGSGNANGGPTSHSSSDLT-RLVGTTTSGQSHKMRSYASSSSSSGVLAGSAGSY 905
Fly 906 SKSLSQNLSRGSSKSNCSGPYDSLDFALPSGKGSLPSCMGSSSMLAT-PTPASASPAGISSEHSS 969
Fly 970 ERSLYGSHNSCIHMPGALPLGLGLPQSSASTPTPNPTPPPNGGGVTFLDKRSPIHFREGRRASDG 1034
Fly 1035 LVAQGLLSSGSLLGTSRVYGSYRYEQAKRHGWLEIQQLQQLQQEAAVGHSHPHAHQHPHQHPHPH 1099
Fly 1100 PQAYGLEELC-QFPNGQ-------FYALPGKHHPLLTLPHHHAHPAQH---HHGHHSLFHSGHQA 1153
Fly 1154 TPLLLEAAAGGDMYGHGCYAPPPPPPGLYTHHQLGVGMAVPMSPMQKPPLQQQLLQHRLLQQKRQ 1218
Fly 1219 LFQKQYALEAQLAGRHHHHQQHSHHHHHHFGHSL-----GPPPPPAPAPEHHLADELYELALLDR 1278
Fly 1279 PRSGTPRLQHSMTMPGAHAFSQMNLK---------------TSYISQSDQVPGAAPNGAGSGGSA 1328
Fly 1329 AGV-----SCSAP--PSTAPGTPTVKCK-------------PTTPHGHSLDSDYHTSTPVLSLFT 1373
Fly 1374 PNWQSLVKPLSESPILEISEHLESV 1398 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sik2 | NP_569972.1 | STKc_SIK | 140..392 | CDD:270973 | 198/251 (79%) |
| S_TKc | 141..392 | CDD:214567 | 197/250 (79%) | ||
| SIK2 | NP_056006.1 | STKc_SIK | 19..271 | CDD:270973 | 198/251 (79%) |
| UBA_SIK2 | 297..341 | CDD:270592 | 20/44 (45%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 644..666 | 3/21 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 742..776 | 8/33 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 801..896 | 17/95 (18%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165158953 | |
| Domainoid | 1 | 1.000 | 421 | 1.000 | Domainoid score | I628 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0586 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 504 | 1.000 | Inparanoid score | I1352 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000311 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41733 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105552 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24343 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5859 |
| SonicParanoid | 1 | 1.000 | - | - | X2250 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.780 | |||||