Protein Alignment Sik2 and mark3

DIOPT Version :9

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: XP_031747282.1
• Gene: mark3 / 100329119
• XenbaseID: XB-GENE-867495
• Length: 794
• Species: Xenopus tropicalis
• Alignment Length: 804
• Identity: 277/804 - (34%)
• Similarity: 387/804 - (48%)
• Gaps: 220/804 - (27%)

  Fly   134 EPMRVGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYREVEIMKRLKHP 198
            |...:|.|.:.:||||||||.||||||.:|..|||||||||:||:.|:|||::|||.|||.|.||
 Frog    49 EQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHP 113

  Fly   199 HIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRD 263
            :|:||::|:||:..:|:|.||||.||:|||:..:|||.|..||.||.||:|||:|||:|.|||||
 Frog   114 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRD 178

  Fly   264 LKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVL 328
            |||||||||.:||||||||||||.|..|..|.|:||||||||||:|:||:|.|||:|:|||||:|
 Frog   179 LKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL 243

  Fly   329 YVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRWMC 393
            |.||.|:|||||..|:.||:|||.|::||||:||::||:|::|.|||.|::|.|::||.:.||:
 Frog   244 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPSKRGTLEQIMKDRWI- 307

  Fly   394 PELLEHVLIAKYNLGAER---QTSVEPSEDI-----LRIMAEYVGIG--SDKTRASLKKNTYDHV 448
                        |.|.|.   :..|||..||     :.||   ||:|  .::.:.||.|..||.:
 Frog   308 ------------NAGHEEDELKPFVEPELDISDQKRIDIM---VGMGYSREEIQESLSKMKYDEI 357

  Fly   449 AAIYLLLQDRVSHKKEQSNGLGASALASSTSASRMIYSSRND-HQPTQQQSQQQSKTISTSSILA 512
            .|.||||       ..:|:.|.||..:||::.|.......:| :..:.|....:.::||:|
 Frog   358 TATYLLL-------GRKSSELDASDSSSSSNLSLAKVRPNSDLNNSSGQSPHHKGRSISSS---- 411

  Fly   513 KDQCHKRLSRHQTVLMSERNAHAGATPTVPDPGPGYYAKYGPLQLPLPLTGHSHLTGYLNGGGVE 577
              |..:|.|.|             |.|.||.                       :|.|
 Frog   412 --QKQRRYSDH-------------AGPAVPS-----------------------VTAY------- 431

  Fly   578 VDASGIPLPMRYTPLPTAASPAPSNCSSTSS----RVGRHSLSSSSPRSHRPVAISLSIDNNPSL 638
                                |..|..|:|.:    .||:...|||:.|...|.:..|...:||:.
 Frog   432 --------------------PKRSQTSTTDNDLKDEVGQSRKSSSTGRGVTPPSPMLGNASNPNK 476

  Fly   639 ANLRCREMMEAGGGPVGAVGVPLASKQLHQTISEFIIKQSTEDC--RALLQQSTAVAEGKDDPPK 701
            |::..|:....         ||.::     :.|..:.:::|..|  ||...:.:.:..||
 Frog   477 ADIPERKKSSV---------VPTSN-----STSSGMTRRNTYVCSERAPTDRHSVIQNGK----- 522

  Fly   702 AESSVGGV----PPPASTTPTSS--------------------------TAGPESGSAPCPGE-- 734
             |:|:.|:    ..|||....||                          :.|...|.|..|.:
 Frog   523 -ENSLTGIFTYATSPASVCAISSIFARLRHPKSMSMSASRHSEMLPPIASEGDNFGPATIPDQRT 586

  Fly   735 -------INGKTI-------KTMSSSSSFDSKANLGQSFRY-------KMSAEASKLFQTLQESP 778
                   |...|.       :..:|.|:|..:....::..|       .:|.||:.|.||.....
 Frog   587 SVASTHSITSTTTPDRMRFPRGTASRSTFHGQLRERRTATYNGPPASPSLSHEATPLSQTRSRGS 651

  Fly   779 --------------LPVEQRTKRRVHVGSTNGSGGDSGQETNDAK-----------------SNG 812
                          ||.|.....| :.||:....||...|..::|                 .|.
 Frog   652 TNLFSKLTSKLTRRLPTESERNGR-YEGSSRNVSGDQKDENKESKPRSLRFTWSMKTTSSMDPND 715

  Fly   813 DSRSEKKVLAQGSSSTDEGCETDQ 836
            ..|..:|||...:      |:.:|
 Frog   716 MMREIRKVLDANN------CDYEQ 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	163/251 (65%)
		S_TKc	141..392	CDD:214567	163/250 (65%)
mark3	XP_031747282.1	STKc_MARK	55..307	CDD:270974	163/251 (65%)
		UBA_MARK3_4	325..367	CDD:270590	17/51 (33%)
		MARK1-3_C	695..792	CDD:213381	8/45 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000311
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000