Protein Alignment Sik2 and Gm4567

DIOPT Version :9

• Sequence 1: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Sequence 2: NP_001032325.1
• Gene: Gm4567 / 100043645
• MGIID: 3809658
• Length: 301
• Species: Mus musculus
• Alignment Length: 270
• Identity: 117/270 - (43%)
• Similarity: 167/270 - (61%)
• Gaps: 13/270 - (4%)

  Fly   130 LKLKEPMRVGFYDIE----------RTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQK 184
            ||:.|......|.||          .|:|:|.|:|||.|.|..|...||:||:..:: :.|:  .
Mouse     6 LKMMEQDLKACYSIEENFDTNYKMLNTLGEGKFSVVKRAFHVPTSTSVAVKILQNTK-EYTS--P 67

  Fly   185 VYREVEIMKRLKHPHIIKLYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIIS 249
            :.||..|||.|.||:||||:.|::.:...|:|.||||:||:.|.|.|.|.:.||..|..|.||:.
Mouse    68 ICREARIMKSLSHPNIIKLFHVVQRRETTYLVMEYASEGELQDRIIKVGSLEESETRRLFAQIVH 132

  Fly   250 AVEYCHKKGIVHRDLKAENLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQY 314
            ||:|||...|||||:||.|:|:|...|.|:.|||.:....||:.||.:||:.||.|||:.:.::|
Mouse   133 AVQYCHDHHIVHRDIKASNILIDYRGNAKLCDFGLAAEVIPGQKLAGFCGTLPYCAPELLQAEKY 197

  Fly   315 TGPEIDIWSLGVVLYVLVCGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTR 379
            .||.:|||||||:|:::|.|.|||.|.....|:..::|..|.||..:|.:..::|..:|::.|:|
Mouse   198 EGPPVDIWSLGVLLFLMVSGNLPFQGRYFVDLKQEIISANFSIPSHVSIDILNVIIELLMINPSR 262

  Fly   380 RYTIDQIKRH 389
            |.||.||.||
Mouse   263 RPTIHQIMRH 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	114/260 (44%)
		S_TKc	141..392	CDD:214567	114/259 (44%)
Gm4567	NP_001032325.1	STKc_AMPK-like	26..273	CDD:270905	111/250 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810