Protein Alignment moody and gpr25

DIOPT Version :9

• Sequence 1: NP_001188534.1
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_001335309.4
• Gene: gpr25 / 795188
• ZFINID: ZDB-GENE-141216-12
• Length: 377
• Species: Danio rerio
• Alignment Length: 465
• Identity: 95/465 - (20%)
• Similarity: 166/465 - (35%)
• Gaps: 148/465 - (31%)

  Fly     6 TISLEDGYP---PLEALTT----MVPPADATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLK 63
            |:||...|.   |:.:...    .:|.|:....|.   .:..|:..::.:.|..|||..:|.:.|
Zfish    13 TMSLTSEYDYDYPINSTDENPIYTLPDAELLPMSN---IYIPVLYIIMFLTGSLGNLFVIVVIGK 74

  Fly    64 -CPKVRNVAAAFIISLCIADLLFCALVLPFQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCI 127
             ..|...:...|:::|.:|||:| .|.||...:......|..|:|||::..||...|...::..:
Zfish    75 RRKKSGRLVDTFVLNLALADLVF-VLTLPMWAISTRYDEWPFGEVLCKISSFIIAVNRFSNIFFL 138

  Fly   128 AMITINRYVMITHHGLYARIYKRHWI------AVMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQ 186
            ..::::||:.:      .|:....::      .:.....|:.|:.:..|:|       .| ..|.
Zfish   139 TCMSVDRYLAV------VRLMDSRFLRSSNCAQITCGIVWVVSFFLGSPSL-------AY-RHLI 189

  Fly   187 TCSIMTDDHGHS-----SKTTLFITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNN 246
            ..|:.::|...|     :..|:.:| |::|.|::..||..|.       ..|:||...    |.|
Zfish   190 NNSVCSEDSKSSFVQGMNLLTILLT-FLLPVLILGLCYGSIL-------VNLRRHCHN----PAN 242

  Fly   247 LRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRI 311
            .|                       :|:....|:
Zfish   243 TR-----------------------TDARRRHSV------------------------------- 253

  Fly   312 TKMVLAIFLSFVVCYLPITIVKV---------ADKN-----VEHPSLHICSYILLYLSACINPII 362
             |:|.||..:|::.:||....|.         .|.|     |.|..| :.|..|.:|::|:||.|
Zfish   254 -KIVFAIISAFLISWLPFNCFKAIHVALLIINGDLNEDTYVVIHRGL-MLSCCLAFLNSCVNPAI 316

  Fly   363 YVIMNKQYRKAYKTVVFCQPARLLLPFGKTNGASSAAEKWKDTGLSNN---HSRTIVS-QMSGGT 423
            |..:::.:|:  :..:.|...                       ||.|   |...|.| ..|.||
Zfish   317 YFFLDQHFRR--RASMLCLSC-----------------------LSQNDQAHQSYITSNSYSNGT 356

  Fly   424 GAASGAGTAT 433
            .......|:|
Zfish   357 SETCSGNTST 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_001188534.1	7tm_4	44..>167	CDD:304433	29/129 (22%)
		7tm_1	53..363	CDD:278431	70/335 (21%)
		7tm_4	<310..380	CDD:304433	22/83 (27%)
gpr25	XP_001335309.4	7tmA_GPR25	48..328	CDD:320321	75/364 (21%)
		TM helix 1	49..75	CDD:320321	6/25 (24%)
		TM helix 2	83..108	CDD:320321	9/25 (36%)
		TM helix 3	120..150	CDD:320321	6/35 (17%)
		TM helix 4	163..184	CDD:320321	4/27 (15%)
		TM helix 5	203..232	CDD:320321	8/36 (22%)
		TM helix 6	247..277	CDD:320321	9/61 (15%)
		TM helix 7	296..321	CDD:320321	10/25 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24228
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100