Protein Alignment moody and Gpr88

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_113884.1
• Gene: Gpr88 / 64443
• RGDID: 61921
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 419
• Identity: 95/419 - (22%)
• Similarity: 168/419 - (40%)
• Gaps: 117/419 - (27%)

  Fly    46 IMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALVLPFQ--------GLRFVQGTW 102
            :.|.|...|.:.:..:....|::..:.|||::.|.|||..|||.:|.:        |.....|.|
  Rat    41 LAIGGTLANGMVIYLVSSFRKLQTTSNAFIVNGCAADLSVCALWMPQEAVLGLLPAGSAEPPGDW 105

  Fly   103 RHGQVLCRLIPFIQYGNIG----VSLLCIAMITINRYVMITH-HGLYARIYKRHWIAVMIAACWL 162
            ..|....||   ::.|.:|    ||||...::.:|||::||. ...|..:|:|...|.|:|..|.
  Rat   106 DSGGGSYRL---LRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQVLYQRRHTAGMLALSWA 167

  Fly   163 FSYGMQLPTLLGEWG--------RFGYDSRLQTCSIMTDDHGHSSKTTLFITAFVIPCLVIIACY 219
            .:.|:.|  ||..|.        :..|.:.|...:::       ::|.|           ::.||
  Rat   168 LALGLVL--LLPPWAPKPGAEPPQVHYPALLAAGALL-------AQTAL-----------LLHCY 212

  Fly   220 AKIFWVVHKSEQRLKRHATKQNSIPN----NLRPLASTGSGALP-------SGAECQPSNRVSSD 273
            ..|.        |..|.:.|:.|:.|    :..|..:..:.|.|       :|....|:.
  Rat   213 LGIV--------RRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPAAPHAPGAGGAAHPAQ----- 264

  Fly   274 SSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITKM-VLAIFLSFVVCYLPITIVKVADK 337
                     |:..|:..|            .:|.:.|::.: ||.:...|::...|:..|.:|..
  Rat   265 ---------PQPLPAALQ------------PRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASG 308

  Fly   338 -NVEHP-SLHICSYILLYLSACINPIIYVIMNKQYRKAYKTVVFCQPARLLLPFGKTNGASSAAE 400
             ::..| .:...|::|....:.:||::|...|:::|::.::|         || |..:.|::||
  Rat   309 FSLPVPWGVQAASWLLCCALSALNPLLYTWRNEEFRRSVRSV---------LP-GVGDAAAAAA- 362

  Fly   401 KWKDTGLSNNHSRTIVSQMSG---GTGAA 426
                       :.|.|..||.   ||.||
  Rat   363 -----------AATAVPAMSQAQLGTRAA 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	80/362 (22%)
		TM helix 1	38..64	CDD:320338	3/17 (18%)
		TM helix 2	71..94	CDD:320338	11/30 (37%)
		TM helix 3	109..139	CDD:320338	11/33 (33%)
		TM helix 4	153..171	CDD:320338	6/17 (35%)
		TM helix 5	196..305	CDD:320338	18/119 (15%)
		TM helix 6	306..336	CDD:320338	7/30 (23%)
		TM helix 7	342..367	CDD:320338	6/25 (24%)
Gpr88	NP_113884.1	7tm_GPCRs	33..347	CDD:475119	80/362 (22%)
		TM helix 1	34..58	CDD:320339	3/16 (19%)
		TM helix 2	67..89	CDD:320339	11/21 (52%)
		TM helix 3	114..136	CDD:320339	7/24 (29%)
		TM helix 4	160..176	CDD:320339	5/17 (29%)
		TM helix 5	190..213	CDD:320339	5/40 (13%)
		TM helix 6	283..305	CDD:320339	5/21 (24%)
		TM helix 7	315..340	CDD:320339	5/24 (21%)