Protein Alignment moody and BDKRB2

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_000614.1
• Gene: BDKRB2 / 624
• HGNCID: 1030
• Length: 391
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 90/438 - (20%)
• Similarity: 152/438 - (34%)
• Gaps: 166/438 - (37%)

  Fly    10 EDGYPPLEA-------LTTMVPPADATGFSQS----------LLTFAAVMTFLIMIVGICGNL-- 55
            ||..|...:       :|...|..:.| |:||          |.|......:::.::....|:
Human    15 EDSVPTTASFSADMLNVTLQGPTLNGT-FAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFV 78

  Fly    56 LTVVALLK--CPKVRNVAAAFIISLCIADLLFCALVLPFQGLRFVQG-TWRHGQVLCRLIPFIQY 117
            |:|..|.|  |    .||..::.:|..|||:. |..|||..:..... .|..|:.|||::..|..
Human    79 LSVFCLHKSSC----TVAEIYLGNLAAADLIL-ACGLPFWAITISNNFDWLFGETLCRVVNAIIS 138

  Fly   118 GNIGVSLLCIAMITINRYVMITHHGLYARIYKRHWIAVMIAACW----LFSYGMQLPTLLGEWGR 178
            .|:..|:..:.:::|:||:.:.......|:....|..:.....|    |.|..|.:...:.|:
Human   139 MNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEY-- 201

  Fly   179 FGYDSRLQTCSIMTDDHGHS----------------SKTTLFITAFVIPCLVIIACYAKIFWVVH 227
                          .|.||:                :...|.:..|::|..||..|..:|..|:.
Human   202 --------------SDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLR 252

  Fly   228 KSE-QRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQ 291
            .:| |:.|
Human   253 NNEMQKFK--------------------------------------------------------- 260

  Fly   292 QPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKVADKNVEHPSLH----------- 345
                     |::.:|   |.|.:||.:.|.|::|:||..|....|      :||
Human   261 ---------EIQTER---RATVLVLVVLLLFIICWLPFQISTFLD------TLHRLGILSSCQDE 307

  Fly   346 --------ICSYILLYLSACINPIIYVIMNKQYRK----AYKTVVFCQ 381
                    |.|: :.|.::|:||::|||:.|::||    .|:.|  ||
Human   308 RIIDVITQIASF-MAYSNSCLNPLVYVIVGKRFRKKSWEVYQGV--CQ 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	76/385 (20%)
		TM helix 1	38..64	CDD:320338	5/29 (17%)
		TM helix 2	71..94	CDD:320338	9/22 (41%)
		TM helix 3	109..139	CDD:320338	8/29 (28%)
		TM helix 4	153..171	CDD:320338	4/21 (19%)
		TM helix 5	196..305	CDD:320338	14/125 (11%)
		TM helix 6	306..336	CDD:320338	11/29 (38%)
		TM helix 7	342..367	CDD:320338	11/43 (26%)
BDKRB2	NP_000614.1	7tmA_BK-2	58..343	CDD:320503	76/381 (20%)
		TM helix 1	59..85	CDD:320503	3/25 (12%)
		TM helix 2	92..117	CDD:320503	9/25 (36%)
		TM helix 3	130..160	CDD:320503	8/29 (28%)
		TM helix 4	173..194	CDD:320503	5/20 (25%)
		TM helix 5	221..250	CDD:320503	7/28 (25%)
		TM helix 6	263..293	CDD:320503	11/32 (34%)
		TM helix 7	311..336	CDD:320503	9/25 (36%)